Protein Alignment CG14142 and MINDY4

DIOPT Version :9

• Sequence 1: NP_648447.2
• Gene: CG14142 / 39261
• FlyBaseID: FBgn0036143
• Length: 447
• Species: Drosophila melanogaster
• Sequence 2: NP_115598.2
• Gene: MINDY4 / 84182
• HGNCID: 21916
• Length: 757
• Species: Homo sapiens
• Alignment Length: 426
• Identity: 114/426 - (26%)
• Similarity: 177/426 - (41%)
• Gaps: 84/426 - (19%)

  Fly    12 PITAELATDLRNLVFGTAAIPMRAEWLQTSFVFGAPKEELAYGLRSPRNATRGLLSVVQGFVLKY 76
            ||...:|.:::.|:||::......||...||.| :....|.||:...:....|:|:.|||.||:.
Human   406 PIDLSVAKEIKTLLFGSSFCCFNEEWKLQSFSF-SNTASLKYGIVQNKGGPCGVLAAVQGCVLQK 469

  Fly    77 LLFARKTSRVASLTDPLLATADMQREALFCALLEILRTISDKGKVTMVLPSEDEVFVDHSACYFH 141
            |||...:.  |.....|..:...:...|..||.:|:.....:.:..:.|.|..:.| ..:..|..
Human   470 LLFEGDSK--ADCAQGLQPSDAHRTRCLVLALADIVWRAGGRERAVVALASRTQQF-SPTGKYKA 531

  Fly   142 DSVTEKLYVFTLSPNDELEYFLKRNFKYFTEEETP-GTLLFLYSAVLTRSMGKVRTDLDSAKSTP 205
            |.|.|.|.:.:|:..::|..||:::...|  |..| |.:|...||:|:||...:|.|.|...|..
Human   532 DGVLETLTLHSLTCYEDLVTFLQQSIHQF--EVGPYGCILLTLSAILSRSTELIRQDFDVPTSHL 594

  Fly   206 LTSSNHEEGSLMIVTLLLTGRATPYIHNGVVNVGDESSYAVPQYGVLKRCMIGLLLWDIESASAA 270
            :.:  |...:..:|.|||||:|...:.|.||.:...........|:..|..||.|     |....
Human   595 IGA--HGYCTQELVNLLLTGKAVSNVFNDVVELDSGDGNITLLRGIAARSDIGFL-----SLFEH 652

  Fly   271 VNQSRQPGSRLKTPNYPIWITSCTGHFGVIFNKNPDLLRNYHAESRFDVNYY---SCSGHQILMT 332
            .|.. |.|..||||.:|||:.....||.::|:..|.|||::..|..||:.||   :....||.:|
Human   653 YNMC-QVGCFLKTPRFPIWVVCSESHFSILFSLQPGLLRDWRTERLFDLYYYDGLANQQEQIRLT 716

  Fly   333 IDNRTYNEQALVMLERQPITPESTSMSGKEDGGGATSPTTVSGGGGAAAGGGVGGASGGVGGAAS 397
            ||                     |:.:..||
Human   717 ID---------------------TTQTISED---------------------------------- 726

  Fly   398 GASGGNDVVAKEESTLNTPLQRLIRTKWEEATISFH 433
               ..||:|        .||:..|||||:.|:::::
Human   727 ---TDNDLV--------PPLELCIRTKWKGASVNWN 751

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14142	NP_648447.2	DUF4205	22..433	CDD:290609	111/414 (27%)
MINDY4	NP_115598.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	152..173
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	190..334
		DUF4205	416..752	CDD:290609	111/416 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146964
Domainoid	1	1.000	146	1.000	Domainoid score	I4550
eggNOG	1	0.900	-	-		E1_KOG2871
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1276386at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm42093
orthoMCL	1	0.900	-	-		OOG6_104874
Panther	1	1.100	-	-	LDO	PTHR12473
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6307
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.750