DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG14142 and AQP9

DIOPT Version :9

Sequence 1:NP_648447.2 Gene:CG14142 / 39261 FlyBaseID:FBgn0036143 Length:447 Species:Drosophila melanogaster
Sequence 2:NP_066190.2 Gene:AQP9 / 366 HGNCID:643 Length:295 Species:Homo sapiens


Alignment Length:73 Identity:18/73 - (24%)
Similarity:27/73 - (36%) Gaps:29/73 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly   214 GSLMIVTL---------LLTGRATPYIHNGV--VNVGDESSYAVPQY---GV----------LKR 254
            |:.:::.|         |..||     ..||  :|||...:.|:..|   ||          |..
Human    32 GTFILIVLGCGCVAQAILSRGR-----FGGVITINVGFSMAVAMAIYVAGGVSGGHINPAVSLAM 91

  Fly   255 CMIGLLLW 262
            |:.|.:.|
Human    92 CLFGRMKW 99

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14142NP_648447.2 DUF4205 22..433 CDD:290609 18/73 (25%)
AQP9NP_066190.2 MIP 1..266 CDD:294134 18/73 (25%)
NPA 1. /evidence=ECO:0000250|UniProtKB:Q96PS8 84..86 0/1 (0%)
NPA 2. /evidence=ECO:0000250|UniProtKB:Q96PS8 216..218
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2356
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.030

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