Protein Alignment CG14142 and AQP1

DIOPT Version :9

• Sequence 1: NP_648447.2
• Gene: CG14142 / 39261
• FlyBaseID: FBgn0036143
• Length: 447
• Species: Drosophila melanogaster
• Sequence 2: NP_001316801.1
• Gene: AQP1 / 358
• HGNCID: 633
• Length: 323
• Species: Homo sapiens
• Alignment Length: 411
• Identity: 78/411 - (18%)
• Similarity: 129/411 - (31%)
• Gaps: 143/411 - (34%)

  Fly    17 LATDLRNLVFGTAAIPMRAEWLQTS-FVF---GAPKEELAYGLRSP----RNATRGLLSVVQGFV 73
            :|::.:..:|..|.:   ||:|.|: |||   |:     |.|.:.|    :.|.:..:.|...|.
Human     1 MASEFKKKLFWRAVV---AEFLATTLFVFISIGS-----ALGFKYPVGNNQTAVQDNVKVSLAFG 57

  Fly    74 LKYLLFARKTSRVA------SLTDPLLATADMQREALFCALLEILRTISDKGKVTMVLPSEDEVF 132
            |.....|:....::      ::|..||.:..:   ::|.||:.|:.........|.:|
Human    58 LSIATLAQSVGHISGAHLNPAVTLGLLLSCQI---SIFRALMYIIAQCVGAIVATAIL------- 112

  Fly   133 VDHSACYFHDSVTEKLYVFTLSPNDELEYFLKRNFKYFTEEETPGTLLFLYSAVLTRSMGKVRTD 197
                     ..:|..|...:|..||..:..   |.......|..|||..:...:.|..  :.|.|
Human   113 ---------SGITSSLTGNSLGRNDLADGV---NSGQGLGIEIIGTLQLVLCVLATTD--RRRRD 163

  Fly   198 LDSAKSTPLTSSNHEEGSLMIVTLLLTGRATPYIHNGVVNVGDESSYAVPQYGVLKRCMIGLL-- 260
            |..  |.||.                                                 |||.
Human   164 LGG--SAPLA-------------------------------------------------IGLSVA 177

  Fly   261 ---LWDIESASAAVNQSRQPGSRLKTPNYP----IWITSCTG-------HFGVIFNKNPDL---- 307
               |..|:.....:|.:|..||.:.|.|:.    .|:....|       :..::..::.||
Human   178 LGHLLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTDRV 242

  Fly   308 -------LRNYHAESRFDVNYYSCSGHQILMTIDNRTYNEQALVMLERQPITPESTSMSGKEDGG 365
                   :..|..::. |:|..|..|.:|.....:....|:   :.||.|    ..|...:.||.
Human   243 KVWTSGQVEEYDLDAD-DINSRSFLGTKIYQFTHSLEVVEE---VKERDP----PASRPSEHDGR 299

  Fly   366 GA-----------TSPTTVSG 375
            .|           .||..|.|
Human   300 CARKSPLAPKLLTDSPAQVPG 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14142	NP_648447.2	DUF4205	22..433	CDD:290609	77/406 (19%)
AQP1	NP_001316801.1	NPA 1	76..78		0/1 (0%)
		NPA 2	192..194		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2356
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.030