DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14142 and Mindy4

DIOPT Version :9

Sequence 1:	NP_648447.2	Gene:	CG14142 / 39261	FlyBaseID:	FBgn0036143	Length:	447	Species:	Drosophila melanogaster
Sequence 2:	NP_001136253.1	Gene:	Mindy4 / 330323	MGIID:	3583959	Length:	744	Species:	Mus musculus

Alignment Length:	428	Identity:	115/428 - (26%)
Similarity:	182/428 - (42%)	Gaps:	88/428 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 PITAELATDLRNLVFGTAAIPMRAEWLQTSFVFGAPKEELAYGLRSPRNATRGLLSVVQGFVLKY 76
            ||...||.:::.|:||:.......||...:|.|. ....|.||:...:....|:|:.|||.||:.
Mouse   393 PIDLSLAKEIKTLLFGSTFCCFSEEWKLQNFSFN-DIASLKYGIVQNKGGPCGVLAAVQGCVLQK 456

  Fly    77 LLFARKTSRVASLTDPLLATADMQR-EALFCALLEILRTISDKGKVTMVLPSEDEVFVDHSACYF 140
            |||.......::|.   |..:|.|| ..|..|:.:||.....|.:..:.|.|....| ..:..|.
Mouse   457 LLFEGDNRTNSNLR---LQPSDAQRTRCLALAIADILWRAGGKEQAVVALASGTPHF-SPTGKYK 517

  Fly   141 HDSVTEKLYVFTLSPNDELEYFLKRNFKYFTEEETP-GTLLFLYSAVLTRSMGKVRTDLDSAKST 204
            .|.|.|.|.:::|:.:::|..|::::...|  |..| |.:|...||:|:||:..||.|.|...|.
Mouse   518 ADGVLETLTLYSLTSSEDLVTFIQQSVHQF--EAGPYGCILLTLSAILSRSLELVRQDFDVPTSH 580

  Fly   205 PLTSSNHEEGSLMIVTLLLTGRATPYIHNGVVNVGDESSYAVPQYGVLKRCMIGLL-LWDIESAS 268
            .:.:  |...:..:|.|||||||...:.|.||.:...........|:..|..||.| |::..:..
Mouse   581 LIGA--HGYCTQELVNLLLTGRAVSNVFNDVVELDSGDGNITLLRGIEARSDIGFLSLFEHYNVC 643

  Fly   269 AAVNQSRQPGSRLKTPNYPIWITSCTGHFGVIFNKNPDLLRNYHAESRFDVNYYSCSGHQ---IL 330
                   |.|..||||.:|||:.....||.::|:..|:||.::.:|..||:.||....:|   |.
Mouse   644 -------QVGCFLKTPRFPIWVVCSESHFSILFSLQPELLCDWRSERLFDLYYYDGLANQQEEIR 701

  Fly   331 MTIDNRTYNEQALVMLERQPITPESTSMSGKEDGGGATSPTTVSGGGGAAAGGGVGGASGGVGGA 395
            :|:|..                              .|:|
Mouse   702 LTVDTT------------------------------KTAP------------------------- 711

  Fly   396 ASGASGGNDVVAKEESTLNTPLQRLIRTKWEEATISFH 433
               |...:|:|        .||:..|||||:.|:::::
Mouse   712 ---ADSCSDLV--------PPLELCIRTKWKGASVNWN 738

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14142	NP_648447.2	DUF4205	22..433	CDD:290609	111/416 (27%)
Mindy4	NP_001136253.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	211..358
Mindy4	NP_001136253.1	DUF4205	403..739	CDD:290609	111/418 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836909
Domainoid	1	1.000	141	1.000	Domainoid score	I4704
eggNOG	1	0.900	-	-		E1_KOG2871
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1276386at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm44147
orthoMCL	1	0.900	-	-		OOG6_104874
Panther	1	1.100	-	-	LDO	PTHR12473
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2356
SonicParanoid	1	1.000	-	-		X6307
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.740