Protein Alignment Adck5 and ADCK1

DIOPT Version :10

• Sequence 1: NP_648446.1
• Gene: Adck5 / 39260
• FlyBaseID: FBgn0036142
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_001353416.1
• Gene: ADCK1 / 57143
• HGNCID: 19038
• Length: 580
• Species: Homo sapiens
• Alignment Length: 564
• Identity: 168/564 - (29%)
• Similarity: 272/564 - (48%)
• Gaps: 100/564 - (17%)

  Fly    51 LAYDGIV---------NDFTYCGASVRFVRSLKTAGLIAADYLRLDENDP----EYETKVKLLHK 102
            ||..||.         |||    .:||..|::.|..:|:.|||...::.|    ||......:|.
Human    16 LAASGIYFYSNKYLDPNDF----GAVRVGRAVATTAVISYDYLTSLKSVPYGSEEYLQLRSKVHL 76

  Fly   103 KSAERLLETCLLNGGLYIKVGQGFAAINDILPVEYTSTLSLLQDRCLPTTQADVQKVFRKDFGQL 167
            :||.||.|.|..|.|.:|||||...|::.:||.||||||.:|..:...::..::::|.|:|.|:.
Human    77 RSARRLCELCCANRGTFIKVGQHLGALDYLLPEEYTSTLKVLHSQAPQSSMQEIRQVIREDLGKE 141

  Fly   168 PEEIYQEFDYQPVAAASLAQVFKARLPSGEQVAVKVQYNDLQKRFISDLGTIIFLQDIVEFFFKD 232
            ..:::|.||..|:..||||||.||.|..|..||||||:..::.:...|:..:..|...|:..|.:
Human   142 IHDLFQSFDDTPLGTASLAQVHKAVLHDGRTVAVKVQHPKVRAQSSKDILLMEVLVLAVKQLFPE 206

  Fly   233 YNFGWILNDLRKNLVLELNFLQEGQNAERCAKDMEKFSYVHVPKVHWSYTKTRVLTLEWMDGCKI 297
            :.|.|::::.:|||.|||:||.||:|||:.::.:..|.::.||::||..:..|||.:|::||.::
Human   207 FEFMWLVDEAKKNLPLELDFLNEGRNAEKVSQMLRHFDFLKVPRIHWDLSTERVLLMEFVDGGQV 271

  Fly   298 SDLKTIEKEKLSLKDIDVK---------------------------------------------- 316
            :|...:|:.|:.:.::..:
Human   272 NDRDYMERNKIDVNEVRSRAQGCCAGERGLGQGCPGSACVSRSSEKVSHLLSANDFSSSYHVQAL 336

  Fly   317 -----------LFEAFAEQIFYTGFVHADPHPGNIFVRKNRKNGRADIILLDHGLYEELPQNVRG 370
                       |.:.::|.||..||||.||||||:.|||:...|:|:|:|||||||:.|.:..|.
Human   337 SALATIEISRHLGKMYSEMIFVNGFVHCDPHPGNVLVRKHPGTGKAEIVLLDHGLYQMLTEEFRL 401

  Fly   371 PLCEFWEATVLRQENRMQAAAEKIGIGD-YMRFAEVLFQQ--PIRNRGGGIRGKLTQEDIDHMQE 432
            ..|..|::.:.....|::..::::|.|| |..||.:|..:  ...|||.........||:: ::.
Human   402 NYCHLWQSLIWTDMKRVKEYSQRLGAGDLYPLFACMLTARSWDSVNRGISQAPVTATEDLE-IRN 465

  Fly   433 IARNNFEHIMGTLKEMPRSMLFVVRNLNTVRAISHQHG------DVVNRPRVMARYAQKCLYMQH 491
            .|.|....|...|..:||.||.:::..:.:|.|....|      ..:|..|...|     ...:|
Human   466 NAANYLPQISHLLNHVPRQMLLILKTNDLLRGIEAALGTRASASSFLNMSRCCIR-----ALAEH 525

  Fly   492 NRRSPVQYIRWLSGRIYFEYCLFLSAFKLYLLDWYFNILYLVGR 535
            .:::...:.|    |....   |..||.|    |..|:..|:.|
Human   526 KKKNTCSFFR----RTQIS---FSEAFNL----WQINLHELILR 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adck5	NP_648446.1	ADCK1-like	144..395	CDD:270871	90/307 (29%)
ADCK1	NP_001353416.1	ADCK1-like	117..426	CDD:270871	90/308 (29%)