DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adck5 and Coq8b

DIOPT Version :9

Sequence 1:	NP_001261705.1	Gene:	Adck5 / 39260	FlyBaseID:	FBgn0036142	Length:	557	Species:	Drosophila melanogaster
Sequence 2:	NP_001012065.1	Gene:	Coq8b / 308453	RGDID:	1311356	Length:	528	Species:	Rattus norvegicus

Alignment Length:	392	Identity:	94/392 - (23%)
Similarity:	157/392 - (40%)	Gaps:	94/392 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LGTRIRGKRALNGL--------REANVQKGGRPVL------------RFSLLAAGAGGLAYD-GI 56
            |..|:...:...||        |||.::|..||.|            |.|.||: .||||.. |:
  Rat    42 LAQRVHQDQPGRGLTEDEIRRAREARLRKAPRPQLSDRSRERKVPASRISRLAS-FGGLAVGLGL 105

  Fly    57 VNDFTYCGASVRFVRSLKTAGLIAADYLRLDENDPEYETKVKLLHKKSAERLLETCLLNGGLYIK 121
                   ||.....:.....|.:            ::|.....|.:.:|||:::|.....|..:|
  Rat   106 -------GALAEVTKKSLPGGSL------------QHEGSSPFLTEANAERIVQTLCTVRGAALK 151

  Fly   122 VGQGFAAINDILPVEYTSTLSLLQDRCLPTTQADVQKVFRK-----DF---GQLPEEIYQEF--D 176
            :||                :..:||..|.:.|  :|:||.:     ||   .|:.:.:.:|.  |
  Rat   152 IGQ----------------MLSIQDNSLISPQ--LQRVFERVRQSADFMPRWQMMKVLEEELGKD 198

  Fly   177 YQ---------PVAAASLAQVFKARLPSGEQVAVKVQYNDLQKRFISDLGTIIFL----QDIVEF 228
            :|         |.||||:.||.:..|..|.:||||:||..:.:...||:..::.|    ..:.|.
  Rat   199 WQDKVASLEEVPFAAASIGQVHQGVLKDGTEVAVKIQYPGVAESIQSDVQNLLALLKMSVGLPEG 263

  Fly   229 FFKDYNFGWILNDLRKNLVLELNFLQEGQNAERCAKDMEKFSYVHVPKVHWSYTKTRVLTLEWMD 293
            .|.:.:    |..|::.|..|.::.:|...|:...|.:....:..||.|......||||.:|...
  Rat   264 LFAEQS----LQTLQQELAWECDYRREAACAQTFKKLLADDPFFRVPAVVEELCTTRVLGMELAG 324

  Fly   294 GCKISDLKTIEKEKLSLKDIDVKLFEAFAEQIFYTGFVHADPHPGN-IFVRKNRKNGRADIILLD 357
            |..:...:.:.::  ....|..:|......::|...|:..||:..| ::...:.|     :.|||
  Rat   325 GIPLDQCQGLSQD--IRNQICFQLLRLCLRELFEFRFMQTDPNWANFLYDASSHK-----VTLLD 382

  Fly   358 HG 359
            .|
  Rat   383 FG 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adck5	NP_001261705.1	AarF	98..469	CDD:223733	70/286 (24%)
Adck5	NP_001261705.1	ADCK1-like	144..395	CDD:270871	61/240 (25%)
Coq8b	NP_001012065.1	KxGQ motif. /evidence=ECO:0000250\|UniProtKB:Q8NI60	151..154		1/2 (50%)
		ABC1_ADCK3	171..420	CDD:270872	56/225 (25%)
		AAAS motif. /evidence=ECO:0000250\|UniProtKB:Q8NI60	212..215		2/2 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0661
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810