DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adck5 and coq8b

DIOPT Version :9

Sequence 1:	NP_001261705.1	Gene:	Adck5 / 39260	FlyBaseID:	FBgn0036142	Length:	557	Species:	Drosophila melanogaster
Sequence 2:	XP_002938863.1	Gene:	coq8b / 100489004	XenbaseID:	XB-GENE-956767	Length:	621	Species:	Xenopus tropicalis

Alignment Length:	513	Identity:	125/513 - (24%)
Similarity:	202/513 - (39%)	Gaps:	131/513 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 QRVRQLLSLGTRIRGKRA--LNGLREANVQKG----GR---------------PVLRFSLLAAGA 48
            ::||...|..| .||..|  |...||:.:|||    ||               |..|.|.| |..
Frog   121 RQVRAYRSYST-FRGLTADELKRARESKLQKGTEEQGRSKRQKLSDRARERKVPASRISRL-ANF 183

  Fly    49 GGLAYD-GIVNDFTYCGASVRFVR-SLKTAGLIAADYLRLDENDPEYETKVKLLHKKSAERLLET 111
            ||||.. ||       ||....|: ||....       |.|.|....|:.. ||::.:|||:::|
Frog   184 GGLAVGLGI-------GALTEVVKQSLNREE-------RQDSNHSILESNT-LLNEANAERIVDT 233

  Fly   112 CLLNGGLYIKVGQGFA-AINDILPVEYTSTLSLLQDRC--LPTTQADVQKVFRKDFGQLPEEIYQ 173
            .....|..:|:||..: ..|:.:..:.......::...  :|:.|  :.||...:.|....|..:
Frog   234 LCKVRGAALKIGQMLSLQDNNFISPQLQKIFERVRQSADFMPSWQ--MTKVLEDELGHDWREKLE 296

  Fly   174 EFDYQPVAAASLAQVFKARLPSGEQVAVKVQYNDLQKRFISDLGTI-------------IFLQDI 225
            .|:.:|.||||:.||..|||..|.:||:|:||..:.:...||:..:             :|.::.
Frog   297 YFEERPFAAASIGQVHLARLLDGREVAMKIQYPGIAESINSDVENLLSILKMSVAIPAGLFPENS 361

  Fly   226 VEFFFKDYNFGWILNDLRKNLVLELNFLQEGQNAERCAKDMEKFSYVHVPKVHWSYTKTRVLTLE 290
            |:.             |:|.|..|.::.:|.::|:|....:.|..:..||:|....|..||||:|
Frog   362 VQV-------------LQKELTWECDYTREAKSAKRFRHLLSKDPFFSVPQVIDELTTERVLTME 413

  Fly   291 WMDGCKISDLKTIEKEKLSLKDIDVKLFEAFAEQIFYTGFVHADPHPGNIF--VRKNRKNGRADI 353
            .:.|..:.  :.:|.::.:...|...:.....:::|...|:..||:..|.|  ...|:      :
Frog   414 LVSGVPLD--QCVEMDQETRNQISYNILRLCLQEVFEFHFMQTDPNWSNFFYDTESNK------V 470

  Fly   354 ILLDHGLYEELPQNVRGPLCEFWEATVLRQENRMQAAAEKIGIGDYMRFAEVLFQQPIRNRGGGI 418
            :|||.|...|.                          .||. ..||:        :.|:....|.
Frog   471 MLLDFGASREF--------------------------GEKF-TDDYI--------EVIKAAADGD 500

  Fly   419 RGKLTQ--EDIDHMQEIARNNFEH-------IMGT--LKEMPRSMLFVVRNLNTVRAI 465
            |.|:.|  :|:..:.......||.       |:|.  :.::|    |.....||.|.|
Frog   501 RAKVLQKSQDLKFLTGFETKVFEEAHIDAVMILGEAFVSDVP----FNFGTQNTTRRI 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adck5	NP_001261705.1	AarF	98..469	CDD:223733	90/397 (23%)
Adck5	NP_001261705.1	ADCK1-like	144..395	CDD:270871	61/267 (23%)
coq8b	XP_002938863.1	ABC1_ADCK3	262..512	CDD:270872	69/307 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910