Protein Alignment IRSp53 and baiap2l1b

DIOPT Version :9

• Sequence 1: NP_729679.2
• Gene: IRSp53 / 39258
• FlyBaseID: FBgn0052082
• Length: 1076
• Species: Drosophila melanogaster
• Sequence 2: XP_009298154.1
• Gene: baiap2l1b / 550528
• ZFINID: ZDB-GENE-050417-371
• Length: 485
• Species: Danio rerio
• Alignment Length: 425
• Identity: 106/425 - (24%)
• Similarity: 199/425 - (46%)
• Gaps: 52/425 - (12%)

  Fly     2 EAEEVTKLVDGVYRNILDRFNPGARQLIAAGKSYLKALHGAATASRLFNEALAKIAMNAQQSGTG 66
            :.:||.||.:..|:|::::||||.|.||..||||.||:.....|.:.:.:|::||..||..|...
Zfish     4 DPDEVNKLTESTYKNVMEQFNPGLRNLINLGKSYEKAVSAMVLAGKQYFDAVSKIGENAAVSPVS 68

  Fly    67 -DIGSALMSVVNVNKEIQDQQMNILKAFYVDLLVPLETNLEKDTKVVQHEQKKFLQQHKVRMESY 130
             ::|..||.:.:|::::..:.....:.|:.:::..||...:.|.|.:....|::..:||::.:|.
Zfish    69 RELGVVLMEISDVHRKVNVELEENFRRFHREVIAELERKTDMDVKYMTATFKRYQTEHKMKQDSL 133

  Fly   131 QKAVSTMKKQRKK---KATPENTEKELRSLQLLEDQKKKLDVFCDQSYKNAMTQERRRYGFVLER 192
            :::.|.:||.|:|   :...:...||...|:.|..::..:..|.....:.|:.:|:||:.|::::
Zfish   134 ERSQSDLKKVRRKSQGRNASKYESKENECLETLTHRQMDMQKFIADGCQEALLEEKRRFCFLVDK 198

  Fly   193 QCSIAKHWMVYHTTGKTVIDNNFENWQEIAASREIIPPAAYESGYSTSNGHNNNNISSSSSSGNN 257
            .||.:.....:|...:.::.:|...|||..:....:|    :|..|...|      ..:..|...
Zfish   199 HCSFSHQVSAFHQKARELLSDNLIVWQEKCSDATNVP----DSVLSMIEG------LRTPVSNTP 253

  Fly   258 NTSGNMRRLERIKDGDDDHLQGHGAQLKKSRSIDAPYGDMRTLHERENLSGLGGTGPAHYAQNSL 322
            ..|.:::|..|::...:..:....|..:.|     |..:|.:                  .|:|.
Zfish   254 QPSPSLQRHSRVRANSEAMIPAPPAPPQTS-----PLANMFS------------------QQSSR 295

  Fly   323 PRAKSDFNLALVGTGQSSANKHKIIEEQLATLGDDQRGDQRPLVKALYAYMPSGENQ--LSFEEG 385
            |.:.||:           .|:...:...::........|:||.|:.::.: .||.|.  ||||||
Zfish   296 PDSDSDY-----------LNEDSGLSRSVSMATGLNHIDKRPKVRTIFPH-KSGNNSTLLSFEEG 348

  Fly   386 DRIA-LVGGKAKGWQFGENLRTQHFGWFPVAYTNA 419
            |.|. |:..:..||.:||...|:..||||.:|..|
Zfish   349 DVITLLIPDERDGWLYGELNNTRQRGWFPSSYCRA 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IRSp53	NP_729679.2	I-BAR_IMD	4..222	CDD:153289	61/221 (28%)
		SH3_Irsp53_BAIAP2L	364..419	CDD:212713	24/57 (42%)
baiap2l1b	XP_009298154.1	BAR	6..230	CDD:299863	61/223 (27%)
		SH3	327..382	CDD:302595	23/55 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596412
Domainoid	1	1.000	145	1.000	Domainoid score	I4518
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002273
OrthoInspector	1	1.000	-	-		otm24803
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14206
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1500
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	7.900