Protein Alignment IRSp53 and baiap2l1a

DIOPT Version :10

• Sequence 1: NP_729679.2
• Gene: IRSp53 / 39258
• FlyBaseID: FBgn0052082
• Length: 1076
• Species: Drosophila melanogaster
• Sequence 2: XP_009304868.1
• Gene: baiap2l1a / 387261
• ZFINID: ZDB-GENE-031201-1
• Length: 485
• Species: Danio rerio
• Alignment Length: 588
• Identity: 135/588 - (22%)
• Similarity: 237/588 - (40%)
• Gaps: 140/588 - (23%)

  Fly     3 AEEVTKLVDGVYRNILDRFNPGARQLIAAGKSYLKALHGAATASRLFNEALAKIAMNAQQSGTG- 66
            :|:|.||.:..|:|::::||||.|.|:..||:|.|::.....|.:.:.:||:||..:|..|...
Zfish     5 SEDVNKLTESTYKNVMEQFNPGLRNLVNLGKNYEKSVAAMTFAGKAYFDALSKIGESAAVSPVSR 69

  Fly    67 DIGSALMSVVNVNKEIQDQQMNILKAFYVDLLVPLETNLEKDTKVVQHEQKKFLQQHKVRMESYQ 131
            ::|..||.:..|:|..|.:.....|.|:.:|:..||...:.|||.:....|::..:||::.:...
Zfish    70 ELGVVLMEISEVHKNAQLEMEESFKRFHKELIAELEKKTDMDTKYMTATFKRYQSEHKLKQDFLD 134

  Fly   132 KAVSTMKKQRKKKATPENTEKELRS---LQLLEDQKKKLDVFCDQSYKNAMTQERRRYGFVLERQ 193
            |:.:.:||.|:|.....:::.|::.   ::.:..::..:..|.....|.|:.:|:||:.|::::.
Zfish   135 KSQADLKKLRRKSQGKHSSKYEIKENECMETISSRQTDMQRFIADGCKEALLEEKRRFCFLVDKH 199

  Fly   194 CSIAKHWMVYHTTGKTVIDNNFENWQEIAASREIIPPAAYE--SGYSTSNGHNNNNISSSSSSGN 256
            |:::.....:|...|.::.....:|||.......:|.....  .|..|            |.|..
Zfish   200 CALSYQLSAFHDKAKEMLTVKLPSWQEKCNDATRVPDTVISMIEGLRT------------SMSVI 252

  Fly   257 NNTSGNMRRLERIKDGD-----DDHLQGHGAQLKKSRSIDAP--------YGDMRTLHERENLSG 308
            ..:|..:.|.:|...|.     ...|:.|.:.|....|.:||        |.|..:|.|
Zfish   253 PESSPTLERSDRTNSGSIVPPPAPSLKAHTSPLASMFSQEAPKSPISSEQYSDQDSLDE------ 311

  Fly   309 LGGTGPAHYAQNSLPRAKSDFNLALVGTGQSSANKHKIIEEQLATLGDDQRGDQRPLVKALYAYM 373
                       |.|.|:.|      |.:|..:|.|.:                    |:.::.:
Zfish   312 -----------NGLSRSTS------VSSGMDTAKKTR--------------------VQTIFPH- 338

  Fly   374 PSGENQ--LSFEEGD-RIALVGGKAKGWQFGENLRTQHFGWFPVAYTNAEVAEVTTSGGRRYENM 435
            .:|.|:  ||||:|| .|.|:..:..||.:||...|...||||.:|..:  ...||....|.|:.
Zfish   339 TAGNNETLLSFEDGDIIILLIQEERDGWLYGELEHTGQRGWFPSSYCRS--YNETTIPNSRMESP 401

  Fly   436 LMSY----ERNGGGSGSGSGGGGLRSYQQQQDYEAQLELMESHEATYRRRRNHSAEDSSPTRMFG 496
            ..|:    |                  ||::|.|.:..:::                  |...:.
Zfish   402 FSSHIDLPE------------------QQEEDEEVEEPVLQ------------------PPPDYS 430

  Fly   497 DTIKQQKKYRPGSGANPRPGPPPTLPAPVPNGPQSQSSRMLNSSQSFCASNGGGVNAAVERRKQK 561
            |:            :..||..|.|        |.|||:..|.:..|.....|||...|..|.:..
Zfish   431 DS------------SRDRPIKPST--------PSSQSTVSLANGHSMPPFLGGGNPFATVRLRPT 475

  Fly   562 LLN 564
            :.|
Zfish   476 VTN 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IRSp53	NP_729679.2	I-BAR_IMD	4..222	CDD:153289	59/221 (27%)
		SH3_Irsp53_BAIAP2L	364..419	CDD:212713	21/57 (37%)
baiap2l1a	XP_009304868.1	BAR	6..230	CDD:472257	59/223 (26%)
		SH3_BAIAP2L1	330..387	CDD:212846	21/77 (27%)