Protein Alignment IRSp53 and baiap2b

DIOPT Version :10

• Sequence 1: NP_729679.2
• Gene: IRSp53 / 39258
• FlyBaseID: FBgn0052082
• Length: 1076
• Species: Drosophila melanogaster
• Sequence 2: XP_073774811.1
• Gene: baiap2b / 100537012
• ZFINID: ZDB-GENE-100812-7
• Length: 563
• Species: Danio rerio
• Alignment Length: 522
• Identity: 142/522 - (27%)
• Similarity: 252/522 - (48%)
• Gaps: 73/522 - (13%)

  Fly     4 EEVTKLVDGVYRNILDRFNPGARQLIAAGKSYLKALHGAATASRLFNEALAKIAMNAQQS-GTGD 67
            :||.::.:.||::|:::|||..|..:|.||:|.|||.....|::.:.:||.::...|.:| |:.|
Zfish    13 DEVHRITENVYKSIMEQFNPCLRNFVAMGKTYEKALSSVTFAAKGYFDALVRMGELASESHGSKD 77

  Fly    68 IGSALMSVVNVNKEIQDQQMNILKAFYVDLLVPLETNLEKDTKVVQHEQKKFLQQHKVRMESYQK 132
            :|..|..:..|:::||.|..::||:|:.:||..||..:|.|.:.:....||:..:||.:.||.:|
Zfish    78 LGDVLFQMAEVHRQIQMQLEDMLKSFHNELLTELEKKVELDVRYLNAALKKYQMEHKSKGESLEK 142

  Fly   133 AVSTMKKQRKKKATPENT----EKELRSLQLLEDQKKKLDVFCDQSYKNAMTQERRRYGFVLERQ 193
            ..:.:||.|:|....:|.    :||::.::.:..::.:||.:..:|||||:::|||||.|:::||
Zfish   143 CQAELKKLRRKSQGSKNPSKYGDKEMQYVETISSKQNELDNYISESYKNALSEERRRYCFLVDRQ 207

  Fly   194 CSIAKHWMVYHTTGKTVIDNNFENWQEIAASREIIPPAA------YESGYSTSNGHNNNNISSSS 252
            |::||....|||.|:.::......||:..|....:|..|      ..||.:.:.|.:.::.|.|:
Zfish   208 CAVAKTSNTYHTKGRDLLTQKIPLWQQACADPNKLPERAMLLAQQMSSGAAGTLGPSVHHTSKSN 272

  Fly   253 SSGNNNTSGNM-----RRLERIKDGDDDHLQGHGAQLKKSRSIDAPYGDMRTLHERENLSGLGGT 312
            .:.::...|..     ..|..:.......:.|         :...|..:...:|..|:......|
Zfish   273 LTISDPIPGAKPLPVPPELAALMGNQQSRMMG---------ADSVPIVNGSGVHVGEDYQRWMET 328

  Fly   313 GPAHYAQNSLPRAKSDFNLALVGTGQSSAN------------KHKIIEEQL------ATLGDDQR 359
            ..||..|:..|....         |:|.:|            |:.:.|.|.      .|.|.::.
Zfish   329 RAAHDKQSQQPHRHG---------GESFSNTLPVRKVAPVKPKNTLAETQTLPRSSSMTTGLERN 384

  Fly   360 GDQRPLVKALYAYMPSGENQ--LSFEEGDRIALVGGKAK-GWQFGENLRTQHFGWFPVAYTNAEV 421
            |  |..|:||::: .:|:|.  |||.|||.|.|:..:|: ||.:|||.:.:..||||.:||.. :
Zfish   385 G--RTRVQALFSH-AAGDNSTLLSFTEGDIITLLVPEARDGWHYGENEKNRMRGWFPFSYTRL-I 445

  Fly   422 AEVTTSGGRRYENMLMSYERNGGGSGSGSGGGGLRSYQQ---QQDYEAQLELMESHEATYRRRRN 483
            ||..::      .:.:|.:.|     ..|..|.|...:.   ..||.......:.....:.|:|.
Zfish   446 AEPDSN------KLHVSLQHN-----RSSSTGNLLEREMALPTPDYGMPTRFAQQQSTAHSRQRP 499

  Fly   484 HS 485
            :|
Zfish   500 YS 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IRSp53	NP_729679.2	I-BAR_IMD	4..222	CDD:153289	76/222 (34%)
		SH3_Irsp53_BAIAP2L	364..419	CDD:212713	25/57 (44%)
baiap2b	XP_073774811.1	None