Protein Alignment NaPi-III and PHO89

DIOPT Version :10

• Sequence 1: NP_648441.1
• Gene: NaPi-III / 39255
• FlyBaseID: FBgn0260795
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: NP_009855.1
• Gene: PHO89 / 852599
• SGDID: S000000500
• Length: 574
• Species: Saccharomyces cerevisiae
• Alignment Length: 664
• Identity: 188/664 - (28%)
• Similarity: 309/664 - (46%)
• Gaps: 134/664 - (20%)

  Fly    10 WMVVIGFLIAFVLAFGIGANDVANSFGTSVGSGVLTIRQACVLATICEISGAVLIGYKVSDTMRK 74
            ::..|..|.||:.||.||||||||||.:|:.|..|...||.|||.:||..||||.|.:||.|::.
Yeast     8 YIFAIAMLFAFLDAFNIGANDVANSFASSISSRSLKYWQAMVLAGLCEFLGAVLAGARVSGTIKN 72

  Fly    75 GILEVGLYEGAEEVLMLGCVAALASSAVWLLVATFLKLPISGTHSIVGSTIGFSLVARGVQGL-- 137
            .|::..::.....||||...:||..|:.||..||.:.:|:|.||||||.|||..:.|.|..|:
Yeast    73 NIIDSSIFTNDPAVLMLTMTSALIGSSCWLTFATAIGMPVSTTHSIVGGTIGAGIAAGGANGVVW 137

  Fly   138 KWSTLGTIVGSWFISPVLSGIVSILLFLAIRRFILRAQEPLKAGFRSLPIFYGV----TFFINVI 198
            .||.:..|:.||||:|:|:|.::.::| :|.||.:...:.|:...::..:..||    ||.|..:
Yeast   138 GWSGVSQIIASWFIAPILAGAIAAIVF-SISRFSVLEVKSLERSIKNALLLVGVLVFATFSILTM 201

  Fly   199 SVVLDGPKLLYMDNI-----PTWIALTASFGLSLLVALLTQLVVVPLQRRKI------AKRLRAE 252
            .:|..|...|::|::     ...|.||.:     :.:::..:...|..|||:      .|.:...
Yeast   202 LIVWKGSPNLHLDDLSETETAVSIVLTGA-----IASIVYFIFFYPFYRRKVLDQDWTLKLIDIF 261

  Fly   253 NPVKFNFE--DSVESSPSGSPKKQRRPLSL-VSEGKPLPAIAEITELVSLSDNSPRTFKLAPFGL 314
            ....|.|:  |.:...|.|      ..|:: ..||:     ..:...||:.|...:
Yeast   262 RGPSFYFKSTDDIPPMPEG------HQLTIDYYEGR-----RNLGTTVSVEDEENK--------- 306

  Fly   315 AAKNNNALGEEYKIDPQLIKKAEDLLGKASLDNTDLTITSLNFIDEQQQQQQQQQNGRKLQECFK 379
            ||.|:|          ..:|..||      :...||.
Yeast   307 AASNSN----------DSVKNKED------IQEVDLV---------------------------- 327

  Fly   380 RMQSPKEEQKSKTNSIGTDLETGSTKATNNNLQVVESGGSLDLMISSTLSPNSSKVPLIESKEAL 444
            |.::..|.:.|......:.|:.|..|.......|:..|.:.|::.:.           :..::.|
Yeast   328 RTETEPETKLSTKQYWWSLLKQGPKKWPLLFWLVISHGWTQDVIHAQ-----------VNDRDML 381

  Fly   445 NEQEEELKRTTGGGRRTSGAEETPEISMLFSFLQILTATFGSFAHGGNDVSNAIGPLIALYMIYR 509
            :   .:||   |...|:...:.  .:..::|.||.:||...|||||.|||:||.|||.|:|:|::
Yeast   382 S---GDLK---GMYERSKFYDN--RVEYIYSVLQAITAATMSFAHGANDVANATGPLSAVYVIWK 438

  Fly   510 EGSVMQQAESPIYILIYGGIGISVGLWLWGRRVIETIGNDLTKITSSTGFTIEVGAAITVLLASK 574
            ..::..::|.|:::|.|||:.:.:|.|.:|..:|:.:||.:...:.|.||:||:..|||.::|::
Yeast   439 TNTIGAKSEVPVWVLAYGGVALVIGCWTYGYNIIKNLGNKMILQSPSRGFSIELAVAITTVMATQ 503

  Fly   575 IGLPISTTHCKVGSVVFVGHVSASGRKKKSQPNDQTDKETHNEVAPMDDGSVDWHLFRNIAYAWI 639
            :|:|.|||...||.:|.||                        :...|..||:|.:.......|.
Yeast   504 LGIPTSTTQIAVGGIVAVG------------------------LCNKDLKSVNWRMVAWCYSGWF 544

  Fly   640 VTVPVTALLSAGMM 653
            :|:|:..|: ||::
Yeast   545 LTLPIAGLI-AGII 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NaPi-III	NP_648441.1	PHO4	27..>197	CDD:460184	73/175 (42%)
		PHO4	<464..649	CDD:460184	60/184 (33%)
PHO89	NP_009855.1	PHO4	25..554	CDD:460184	179/642 (28%)