Protein Alignment NaPi-III and Slc20a2

DIOPT Version :10

• Sequence 1: NP_648441.1
• Gene: NaPi-III / 39255
• FlyBaseID: FBgn0260795
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: NP_035524.2
• Gene: Slc20a2 / 20516
• MGIID: 97851
• Length: 656
• Species: Mus musculus
• Alignment Length: 706
• Identity: 293/706 - (41%)
• Similarity: 409/706 - (57%)
• Gaps: 119/706 - (16%)

  Fly     9 LWMVVIGFLIAFVLAFGIGANDVANSFGTSVGSGVLTIRQACVLATICEISGAVLIGYKVSDTMR 73
            ||||::||:|||:|||.:|||||||||||:|||||:|:||||:||:|.|.:|:||:|.||.:|:|
Mouse     7 LWMVILGFIIAFILAFSVGANDVANSFGTAVGSGVVTLRQACILASIFETTGSVLLGAKVGETIR 71

  Fly    74 KGILEVGLYEGAEEVLMLGCVAALASSAVWLLVATFLKLPISGTHSIVGSTIGFSLVARGVQGLK 138
            |||::|.||....|.||.|.|:|:..||||.|:|:||:|||||||.||||||||||||.|.:|::
Mouse    72 KGIIDVNLYNETVETLMAGEVSAMVGSAVWQLIASFLRLPISGTHCIVGSTIGFSLVAIGPKGVQ 136

  Fly   139 WSTLGTIVGSWFISPVLSGIVSILLFLAIRRFILRAQEPLKAGFRSLPIFYGVTFFINVISVVLD 203
            |..|..||.||||||:|||.:|.:||:.||.|||..::|:..|.::||:||..|..|||.|::..
Mouse   137 WMELVKIVASWFISPLLSGFMSGVLFILIRMFILTKEDPVPNGLQALPLFYAATIAINVFSIMYT 201

  Fly   204 GPKLLYMDNIPTWIALTASFGLSLLVALLTQLVVVPLQRRKIAKRLRAENPVKFNFEDSVES-SP 267
            |..:|.: ::|.|.....|||::||.|....|.|.|..:||||.||..|:.:....::|:.. ..
Mouse   202 GAPVLGL-SLPIWAIALISFGVALLFAFFVWLFVCPWMKRKIAGRLEKESALSRASDESLRKVQE 265

  Fly   268 SGSPKKQRRPLSLVSEGKPLPAIAEITELVSLSD-----NSPRTFKLAPFGLA-------AK--- 317
            :.||..:..|.:..|:...:|..:...|.|..|:     |.||    |.:|.|       ||
Mouse   266 AESPGFKELPGAKPSDDSAVPLTSLAGEAVGASEGTSAGNHPR----ASYGRALSMTHGSAKSPI 326

  Fly   318 NNNALGEEYKI------------DPQLIKKAEDLLGKASLDNTDLTITSLNFIDEQQQQQQQQQN 370
            :|...|.|..:            |..|.|   |||.|..:|.            ..:::..|:.|
Mouse   327 SNGTFGFEGHMRNDGHVYHTVHKDSGLYK---DLLHKIHVDR------------GSEEKPTQENN 376

  Fly   371 GRKLQE-----CF----------------KRMQSPKEEQKSKTNSIGTD---LETGSTKATNN-- 409
            .|.|:.     |:                ....:|::.:|...:|:...   |...|..:..|
Mouse   377 YRLLRRNNSYTCYTAAICGMPVHTTFRASDTSSAPEDSEKLVGDSVSYSKKRLRYDSYSSYCNAV 441

  Fly   410 -NLQVVESGGSLDLMISSTLSPNSSKVPLIESKEALNEQEEELKRTTGGGRRTSGAEETPEISML 473
             ..::....|.:::.::|.|:.     |....::...|::||              :::.|:.:|
Mouse   442 AEAEIEAEEGGVEMRLASELAD-----PDRPHEDPTEEEKEE--------------KDSAEVHLL 487

  Fly   474 FSFLQILTATFGSFAHGGNDVSNAIGPLIALYMIYREGSVMQQAESPIYILIYGGIGISVGLWLW 538
            |.|||:|||.||||||||||||||||||:||::||::|.|.|:|.:|:::|.|||:||..|||:|
Mouse   488 FHFLQVLTACFGSFAHGGNDVSNAIGPLVALWLIYQQGGVTQEAATPVWLLFYGGVGICTGLWVW 552

  Fly   539 GRRVIETIGNDLTKITSSTGFTIEVGAAITVLLASKIGLPISTTHCKVGSVVFVGHVSASGRKKK 603
            |||||:|:|.|||.||.|:|||||:.:|.||::||.||||:|||||||||||.||.:    |.:|
Mouse   553 GRRVIQTMGKDLTPITPSSGFTIELASAFTVVIASNIGLPVSTTHCKVGSVVAVGWI----RSRK 613

  Fly   604 SQPNDQTDKETHNEVAPMDDGSVDWHLFRNIAYAWIVTVPVTALLSAGMMYVLCAI 659
                                 :|||.|||||..||.|||||..|.||.:|.:|..|
Mouse   614 ---------------------AVDWRLFRNIFVAWFVTVPVAGLFSAAIMALLMYI 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NaPi-III	NP_648441.1	PHO4	27..>197	CDD:460184	103/169 (61%)
		PHO4	<464..649	CDD:460184	104/184 (57%)
Slc20a2	NP_035524.2	PHO4	25..>224	CDD:460184	113/199 (57%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	257..283		5/25 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	459..478		4/23 (17%)
		PHO4	<480..638	CDD:460184	104/182 (57%)