Protein Alignment NaPi-III and Slc20a1

DIOPT Version :10

• Sequence 1: NP_648441.1
• Gene: NaPi-III / 39255
• FlyBaseID: FBgn0260795
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: NP_056562.1
• Gene: Slc20a1 / 20515
• MGIID: 108392
• Length: 681
• Species: Mus musculus
• Alignment Length: 706
• Identity: 296/706 - (41%)
• Similarity: 414/706 - (58%)
• Gaps: 117/706 - (16%)

  Fly     9 LWMVVIGFLIAFVLAFGIGANDVANSFGTSVGSGVLTIRQACVLATICEISGAVLIGYKVSDTMR 73
            |||:::||:|||||||.:|||||||||||:|||||:|::|||:||:|.|..|:.|:|.|||:|:|
Mouse    26 LWMLILGFIIAFVLAFSVGANDVANSFGTAVGSGVVTLKQACILASIFETVGSALLGAKVSETIR 90

  Fly    74 KGILEVGLYEGAEEVLMLGCVAALASSAVWLLVATFLKLPISGTHSIVGSTIGFSLVARGVQGLK 138
            .|:::|.||...:::||.|.|:|:..||||.|||:||||||||||.|||:||||||||.|.:|:|
Mouse    91 NGLIDVELYNETQDLLMAGSVSAMFGSAVWQLVASFLKLPISGTHCIVGATIGFSLVANGQKGVK 155

  Fly   139 WSTLGTIVGSWFISPVLSGIVSILLFLAIRRFILRAQEPLKAGFRSLPIFYGVTFFINVISVVLD 203
            ||.|..||.|||:||:||||:|.:||..:|.||||..:|:..|.|:|||||..|..||:.|::..
Mouse   156 WSELIKIVMSWFVSPLLSGIMSGILFFLVRAFILRKADPVPNGLRALPIFYACTIGINLFSIMYT 220

  Fly   204 GPKLLYMDNIPTWIALTASFGLSLLVALLTQLVVVPLQRRKIAKRLR---AENPV---KFNF-ED 261
            |..||..|.:|.|..:..|.|.::..||:....|.|..:|||.:.::   :|:|:   |.|. ||
Mouse   221 GAPLLGFDKLPLWGTILISVGCAVFCALIVWFFVCPRMKRKIEREVKSSPSESPLMEKKSNLKED 285

  Fly   262 SVESSPSGSPKKQRRPLS-LVSEGKPLPAIAEITELVSLSDNSPRT--FKLAPFGLAAKNNNA-- 321
            ..|:..:....:.|.|:| :|....||.|:.|           .||  |||.....|.:....
Mouse   286 HEETKMAPGDVEHRNPVSEVVCATGPLRAVVE-----------ERTVSFKLGDLEEAPERERLPM 339

  Fly   322 -LGEEYKIDPQLIKKAEDLLGKASLDNTDL-----TITS-LNFIDEQQQQQQQQQNG-------- 371
             |.||..||       ..:.|...|.|.:|     |::: :|.....|.....:.:|
Mouse   340 DLKEETSID-------STINGAVQLPNGNLVQFSQTVSNQINSSGHYQYHTVHKDSGLYKELLHK 397

  Fly   372 ---RKLQECFKRMQSPKEEQKSKTNS--------IGTDLETGSTKATNNNLQVVESGGSLDLMIS 425
               .|:.:|   |....::...:.||        .|..|::...|      :..:.|..::
Mouse   398 LHLAKVGDC---MGDSGDKPLRRNNSYTSYTMAICGMPLDSFRAK------EGEQKGDEME---- 449

  Fly   426 STLS-PN------------SSKVPLIESKEALNEQEEELKRTTGGGRR--TSGA------EETPE 469
             ||: ||            :|....:....:.:|.:..:|...|.|.|  :||:      ::.||
Mouse   450 -TLTWPNADTKKRIRMDSYTSYCNAVSDLHSESEMDMSVKAEMGLGDRKGSSGSLEEWYDQDKPE 513

  Fly   470 ISMLFSFLQILTATFGSFAHGGNDVSNAIGPLIALYMIYREGSVMQQAESPIYILIYGGIGISVG 534
            :|:||.|||||||.||||||||||||||||||:|||::|:: ....:|.:||::|:|||:||.:|
Mouse   514 VSLLFQFLQILTACFGSFAHGGNDVSNAIGPLVALYLVYKQ-EASTKAATPIWLLLYGGVGICMG 577

  Fly   535 LWLWGRRVIETIGNDLTKITSSTGFTIEVGAAITVLLASKIGLPISTTHCKVGSVVFVGHVSASG 599
            ||:||||||:|:|.|||.||.|:||:||:.:|:||::||.||||||||||||||||.||.:
Mouse   578 LWVWGRRVIQTMGKDLTPITPSSGFSIELASALTVVIASNIGLPISTTHCKVGSVVSVGWL---- 638

  Fly   600 RKKKSQPNDQTDKETHNEVAPMDDGSVDWHLFRNIAYAWIVTVPVTALLSAGMMYV 655
            |.||                     :|||.|||||..||.||||::.::||.:|.|
Mouse   639 RSKK---------------------AVDWRLFRNIFMAWFVTVPISGVISAAIMAV 673

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NaPi-III	NP_648441.1	PHO4	27..>197	CDD:460184	104/169 (62%)
		PHO4	<464..649	CDD:460184	104/190 (55%)
Slc20a1	NP_056562.1	PHO4	44..>203	CDD:460184	97/158 (61%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	266..295		7/28 (25%)
		PHO4	<506..667	CDD:460184	104/186 (56%)
		A	553..560		0/7 (0%)