Protein Alignment NaPi-III and pitr-2

DIOPT Version :10

• Sequence 1: NP_648441.1
• Gene: NaPi-III / 39255
• FlyBaseID: FBgn0260795
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: NP_001343607.1
• Gene: pitr-2 / 181857
• WormBaseID: WBGene00015054
• Length: 494
• Species: Caenorhabditis elegans
• Alignment Length: 650
• Identity: 227/650 - (34%)
• Similarity: 326/650 - (50%)
• Gaps: 188/650 - (28%)

  Fly     8 LLWMVVIGFLIAFVLAFGIGANDVANSFGTSVGSGVLTIRQACVLATICEISGAVLIGYKVSDTM 72
            :||.:::|.::||:|..|:|||||:|:|||||||||||:.||.:||:|.|..|::|:|:.|:|||
 Worm    27 VLWALIVGIILAFLLGNGMGANDVSNAFGTSVGSGVLTMVQAYILASIFEALGSILVGWSVADTM 91

  Fly    73 RKGILEVGLYEGAEEVLMLGCVAALASSAVWLLVATFLKLPISGTHSIVGSTIGFSLVARGVQGL 137
            |||:::...|....:.|:||.||.|...|.|||:||.|.:|:|.|||:||:|||||:|.||::|:
 Worm    92 RKGVVDTSQYADDPKELLLGQVAILGGCAAWLLIATVLHMPVSTTHSLVGATIGFSIVLRGLEGI 156

  Fly   138 KWSTLGTIVGSWFISPVLSGIVSILLFLAIRRFILRAQEPLKAGFRSLPIFYGVTFFINVISVVL 202
            :|.|:..||.|||:||:||||:|.::::.:...:||..:|||.|.|:||:||.|....|.:.|..
 Worm   157 QWMTIVRIVCSWFLSPILSGIISSIIYMIVDHTVLRTGDPLKNGLRALPVFYFVCMAFNALVVFW 221

  Fly   203 DGPKLLYMDNIPTWIALTASFGLSLLVALLTQLVVVPLQRRKIAKRLRAENPVKFNFEDS-VESS 266
            ||.|||:.:.||.|.......|:..:.|.|...|:.|              .:|.|.:.| |:|:
 Worm   222 DGSKLLHFNEIPAWGIAAIVIGVGCVAAALAHFVLKP--------------RIKSNIKGSKVQST 272

  Fly   267 PSGSPKKQRRPLSLVSEGKPLPAIAEITELVSLSDNSPRTFKLAPFGLAAKNNNALGEEYKIDPQ 331
            ||                       ..:::.|.:|
 Worm   273 PS-----------------------RFSDVESAND------------------------------ 284

  Fly   332 LIKKAEDLLGKASLDNTDLTITSLNFIDEQQQQQQQQQNGRKLQECFKRMQSPKEEQKSKTNSIG 396
                :|.|.|                :.||:.|..||:
 Worm   285 ----SEKLKG----------------LPEQKLQNVQQR--------------------------- 302

  Fly   397 TDLETGSTKATNNNLQVVESGGSLDLMISSTLSPNSSKVPLIESKEALNEQEEELKRTTGGGRRT 461
               :|.|.|.....:.::..                                    ||...||
 Worm   303 ---KTPSGKIRKFYVWLLPD------------------------------------RTRVDGR-- 326

  Fly   462 SGAEETPEISMLFSFLQILTATFGSFAHGGNDVSNAIGPLIALYMIYREGSVMQQAESPIYILIY 526
                   .|:.|||.:|:.||.|..||||.|||||||.||.|:..|||..||.|....|||:|:|
 Worm   327 -------NITKLFSTIQVFTACFAGFAHGANDVSNAIAPLAAIISIYRTKSVEQTESVPIYVLLY 384

  Fly   527 GGIGISVGLWLWGRRVIETIGNDLTKITSSTGFTIEVGAAITVLLASKIGLPISTTHCKVGSVVF 591
            |...|.|||||:|..||:|:|.::::|..::|||||.|||:|.|||||:|||:|||||.|||||.
 Worm   385 GVFAICVGLWLFGHYVIKTVGTNMSEINPASGFTIEFGAAMTSLLASKVGLPLSTTHCLVGSVVA 449

  Fly   592 VGHVSASGRKKKSQPNDQTDKETHNEVAPMDDGSVDWHLFRNIAYAWIVTVPVTALLSAGMMYVL 656
            ||.:.:                         :..|.|.:||:||.:|:||:||:.|:|||:|:|:
 Worm   450 VGMIRS-------------------------ENGVKWSIFRDIAISWVVTLPVSGLISAGIMFVI 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NaPi-III	NP_648441.1	PHO4	27..>197	CDD:460184	89/169 (53%)
		PHO4	<464..649	CDD:460184	87/184 (47%)
pitr-2	NP_001343607.1	PHO4	46..482	CDD:460184	215/622 (35%)