DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ufd1-like and UFD1

DIOPT Version :9

Sequence 1:	NP_524023.1	Gene:	Ufd1-like / 39254	FlyBaseID:	FBgn0036136	Length:	316	Species:	Drosophila melanogaster
Sequence 2:	NP_011562.1	Gene:	UFD1 / 852939	SGDID:	S000003280	Length:	361	Species:	Saccharomyces cerevisiae

Alignment Length:	351	Identity:	127/351 - (36%)
Similarity:	186/351 - (52%)	Gaps:	53/351 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 FSGFNMMFPEG-------RNFHANYKCFSVSMLPGNER---TDVEKGGKIIMPPSALDTLTRLNV 58
            ||||: .|..|       :.|...::|:.::|:  |:|   .|...||||.:|||||..|:.||:
Yeast     2 FSGFS-SFGGGNGFVNMPQTFEEFFRCYPIAMM--NDRIRKDDANFGGKIFLPPSALSKLSMLNI 63

  Fly    59 EYPMLFKLTNVKKSRSSHAGVLEFVADEGKCYLPHWMMENLLLGEGDILNIESVSLPVATFSKFQ 123
            .||||||||..:..|.:|.|||||:|:||:.|||.||||.|.:..|.:|.|.|..:|:..|.|.:
Yeast    64 RYPMLFKLTANETGRVTHGGVLEFIAEEGRVYLPQWMMETLGIQPGSLLQISSTDVPLGQFVKLE 128

  Fly   124 PHSTDFLDITNPKAVLENALRNFACLTRGDVIAIKYNKKVYELCVLETKP---GNAVSIIECDMN 185
            |.|.|||||::|||||||.||||:.||..|||.|.||.|.:::.:||.||   ..::.:||.|:.
Yeast   129 PQSVDFLDISDPKAVLENVLRNFSTLTVDDVIEISYNGKTFKIKILEVKPESSSKSICVIETDLV 193

  Fly   186 VEFEAPVGY-----------KDHSETQASGSGQ--------QGAAGTVGGEIAGATNAILEEVVE 231
            .:|..||||           :|..:..:.|.||        ||:..| ..:.||..|:...: :.
Yeast   194 TDFAPPVGYVEPDYKALKAQQDKEKKNSFGKGQVLDPSVLGQGSMST-RIDYAGIANSSRNK-LS 256

  Fly   232 TFKGSGVRLDGKKKKESQLETPVVKKVLARG------VPDYDFQFGLIRFDRNIRPISDRSQEDD 290
            .|.|.|..:.||..|....:.....|:...|      :|:....||.        |:....::::
Yeast   257 KFVGQGQNISGKAPKAEPKQDIKDMKITFDGEPAKLDLPEGQLFFGF--------PMVLPKEDEE 313

  Fly   291 AVAGNADASDAESFHGTGFSMKKTRK 316
            :.||:  .|..::|.|.|.|::|:.|
Yeast   314 SAAGS--KSSEQNFQGQGISLRKSNK 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ufd1-like	NP_524023.1	UFD1	4..316	CDD:227469	126/349 (36%)
Ufd1-like	NP_524023.1	UFD1	17..190	CDD:281187	86/178 (48%)
UFD1	NP_011562.1	UFD1	16..361	CDD:227469	121/336 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341328
Domainoid	1	1.000	173	1.000	Domainoid score	I750
eggNOG	1	0.900	-	-		E1_COG5140
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H39090
Inparanoid	1	1.050	197	1.000	Inparanoid score	I872
Isobase	1	0.950	-	0	Normalized mean entropy	S1050
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003822
OrthoInspector	1	1.000	-	-		oto99178
orthoMCL	1	0.900	-	-		OOG6_101567
Panther	1	1.100	-	-	LDO	PTHR12555
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2330
SonicParanoid	1	1.000	-	-		X2666
TreeFam	1	0.960	-	-
	15	14.730