DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ufd1-like and Ufd1

DIOPT Version :9

Sequence 1:	NP_524023.1	Gene:	Ufd1-like / 39254	FlyBaseID:	FBgn0036136	Length:	316	Species:	Drosophila melanogaster
Sequence 2:	NP_445870.1	Gene:	Ufd1 / 84478	RGDID:	619822	Length:	307	Species:	Rattus norvegicus

Alignment Length:	326	Identity:	186/326 - (57%)
Similarity:	221/326 - (67%)	Gaps:	30/326 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFHFSGFNMMFPE--GRNFHANYKCFSVSMLPG-NERTDVEKGGKIIMPPSALDTLTRLNVEYPM 62
            ||.|:.|:...|.  ...|...|:|||||||.| |:|:||||||||||||||||.|:|||:.|||
  Rat     1 MFSFNMFDHPIPRVFQNRFSTQYRCFSVSMLAGPNDRSDVEKGGKIIMPPSALDQLSRLNITYPM 65

  Fly    63 LFKLTNVKKSRSSHAGVLEFVADEGKCYLPHWMMENLLLGEGDILNIESVSLPVATFSKFQPHST 127
            ||||||....|.:|.||||||||||.||||||||:||||.||.::.:|||:|.|||:|||||.|.
  Rat    66 LFKLTNKNSDRMTHCGVLEFVADEGICYLPHWMMQNLLLEEGGLVQVESVNLQVATYSKFQPQSP 130

  Fly   128 DFLDITNPKAVLENALRNFACLTRGDVIAIKYNKKVYELCVLETKPGNAVSIIECDMNVEFEAPV 192
            |||||||||||||||||||||||.||||||.||:|:|||.|:||||..|||||||||||:|:||:
  Rat   131 DFLDITNPKAVLENALRNFACLTTGDVIAINYNEKIYELRVMETKPDKAVSIIECDMNVDFDAPL 195

  Fly   193 GYKD------HSETQASGSGQQGAAGTVGGEIAGATNAILEEVVETFKGSGVRLDGKKKKESQLE 251
            |||:      |.|:....:...|.||.||              ...|.|||.|||||||......
  Rat   196 GYKEPERPVQHEESIEGEADHSGYAGEVG--------------FRAFSGSGNRLDGKKKGVEPSP 246

  Fly   252 TPVVKKVLARGVPDYDFQFGLIRFDRNIRPISDRSQEDDAVAGNADASDAESFHGTGFSM-KKTR 315
            :|:....:.||:|:|:|:.|.|.|.||.||:..:.:||:| .|...|     |.|.|.|: ||.|
  Rat   247 SPIKPGDIKRGIPNYEFKLGKITFIRNSRPMVKKVEEDEA-GGRFVA-----FSGEGQSLRKKGR 305

  Fly   316 K 316
            |
  Rat   306 K 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ufd1-like	NP_524023.1	UFD1	4..316	CDD:227469	182/321 (57%)
Ufd1-like	NP_524023.1	UFD1	17..190	CDD:281187	132/173 (76%)
Ufd1	NP_445870.1	UFD1	19..193	CDD:281187	132/173 (76%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	230..255		11/24 (46%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	282..307		13/31 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334425
Domainoid	1	1.000	276	1.000	Domainoid score	I1677
eggNOG	1	0.900	-	-		E1_COG5140
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H39090
Inparanoid	1	1.050	336	1.000	Inparanoid score	I2316
OMA	1	1.010	-	-		QHG53647
OrthoDB	1	1.010	-	-		D1134444at2759
OrthoFinder	1	1.000	-	-		FOG0003822
OrthoInspector	1	1.000	-	-		oto96006
orthoMCL	1	0.900	-	-		OOG6_101567
Panther	1	1.100	-	-	LDO	PTHR12555
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2666
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.810