DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ufd1-like and ufd1l

DIOPT Version :9

Sequence 1:	NP_524023.1	Gene:	Ufd1-like / 39254	FlyBaseID:	FBgn0036136	Length:	316	Species:	Drosophila melanogaster
Sequence 2:	NP_001002451.1	Gene:	ufd1l / 436724	ZFINID:	ZDB-GENE-040718-150	Length:	308	Species:	Danio rerio

Alignment Length:	323	Identity:	181/323 - (56%)
Similarity:	216/323 - (66%)	Gaps:	32/323 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 FNMMFPE-GR----NFHANYKCFSVSMLPG-NERTDVEKGGKIIMPPSALDTLTRLNVEYPMLFK 65
            |||..|. ||    .|...|:|:|||||.| |:|:||||||||||||||||.|:|||:.||||||
Zfish     4 FNMFEPHVGRVFQNRFSTQYRCYSVSMLAGPNDRSDVEKGGKIIMPPSALDQLSRLNITYPMLFK 68

  Fly    66 LTNVKKSRSSHAGVLEFVADEGKCYLPHWMMENLLLGEGDILNIESVSLPVATFSKFQPHSTDFL 130
            |||....|.:|.||||||||||.||||||||:||||.||.::.:|||:|.|||:|||||.|.|||
Zfish    69 LTNKNSDRMTHCGVLEFVADEGFCYLPHWMMQNLLLEEGGLVQVESVNLMVATYSKFQPQSPDFL 133

  Fly   131 DITNPKAVLENALRNFACLTRGDVIAIKYNKKVYELCVLETKPGNAVSIIECDMNVEFEAPVGYK 195
            ||||||||||||||||||||.||||||.||:|:|||.|:||||..|||||||||||:|:||:|||
Zfish   134 DITNPKAVLENALRNFACLTTGDVIAINYNEKIYELRVMETKPDKAVSIIECDMNVDFDAPLGYK 198

  Fly   196 D------HSETQASGSGQQGAAGTVGGEIAGATNAILEEVVETFKGSGVRLDGKKKKESQLETPV 254
            :      |.|..|.             |....:|..::.....|.|||.|||||||.......|:
Zfish   199 EPERHMQHPEEPAE-------------EETDPSNYDMDLGFRAFTGSGNRLDGKKKGIEPSPAPL 250

  Fly   255 VKKVLARGVPDYDFQFGLIRFDRNIRPISDRSQEDDAVAGNADASDAESFHGTGFSM-KKTRK 316
            ....:.||:|:|:|:.|.|.|.||.|....::..|:.|      |:..:|.|.|.|: ||.||
Zfish   251 DPSDIKRGIPNYEFKVGRITFIRNARQQPRKTDLDETV------SNFIAFSGEGQSLRKKGRK 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ufd1-like	NP_524023.1	UFD1	4..316	CDD:227469	179/321 (56%)
Ufd1-like	NP_524023.1	UFD1	17..190	CDD:281187	131/173 (76%)
ufd1l	NP_001002451.1	UFD1	1..303	CDD:227469	177/317 (56%)
ufd1l	NP_001002451.1	UFD1	19..193	CDD:281187	131/173 (76%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573452
Domainoid	1	1.000	273	1.000	Domainoid score	I1751
eggNOG	1	0.900	-	-		E1_COG5140
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H39090
Inparanoid	1	1.050	320	1.000	Inparanoid score	I2503
OMA	1	1.010	-	-		QHG53647
OrthoDB	1	1.010	-	-		D1134444at2759
OrthoFinder	1	1.000	-	-		FOG0003822
OrthoInspector	1	1.000	-	-		oto39307
orthoMCL	1	0.900	-	-		OOG6_101567
Panther	1	1.100	-	-	LDO	PTHR12555
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2330
SonicParanoid	1	1.000	-	-		X2666
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800