DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ufd1-like and ufd1

DIOPT Version :9

Sequence 1:	NP_524023.1	Gene:	Ufd1-like / 39254	FlyBaseID:	FBgn0036136	Length:	316	Species:	Drosophila melanogaster
Sequence 2:	NP_596780.1	Gene:	ufd1 / 2539623	PomBaseID:	SPBC16A3.09c	Length:	342	Species:	Schizosaccharomyces pombe

Alignment Length:	340	Identity:	124/340 - (36%)
Similarity:	185/340 - (54%)	Gaps:	57/340 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 GFNMMFPEGRNFHAN--------YKCFSVSMLPGNERTDVEKGGKIIMPPSALDTLTRLNVEYPM 62
            ||:||......||.|        |:|:.|:|:||.||.:|..|||:|:|||||:.|:||||.|||
pombe    13 GFSMMSQLRSAFHNNVNQRFDTRYRCYPVAMIPGEERPNVNYGGKVILPPSALEKLSRLNVSYPM 77

  Fly    63 LFKLTNVKKSRSSHAGVLEFVADEGKCYLPHWMMENLLLGEGDILNIESVSLPVATFSKFQPHST 127
            ||...|....:.:|.|||||:|:||:.|||:|||..|.|..||::.:.:..:...::.|.||.|.
pombe    78 LFDFENEAAEKKTHGGVLEFIAEEGRVYLPYWMMTTLSLEPGDLVRVINTDIAQGSYVKLQPQSV 142

  Fly   128 DFLDITNPKAVLENALRNFACLTRGDVIAIKYNKKVYELCVLETKPGNA---VSIIECDMNVEFE 189
            :|||||:.:||||||||||:.||:.|:..|.||.:||::.|::.:|.::   ||::|.|:.|:|:
pombe   143 NFLDITDHRAVLENALRNFSTLTKSDIFEILYNDQVYQIKVIDVQPDDSRHVVSVVETDLVVDFD 207

  Fly   190 APVGYKDHSETQASGSGQQGAAGTVGGEIAGATNAILEEVV-----ETFKGSGVRLDGKKKKE-- 247
            .|:||    |.....:.||..||..|..:   |....:|:|     ...||:|.:|:||:..|
pombe   208 PPIGY----EESLQKNKQQNIAGVQGTMV---TKIGYDELVRQGDSNLMKGTGTKLNGKEVAEVP 265

  Fly   248 ---------SQLETPVVKKVLARGVPDYDFQFGLIRFDRNIRPISDRSQEDDAVAGNADASDAE- 302
                     .:...|::       :|...:.||.        |....|.|:|:      ..|..
pombe   266 KINLLDVEKQECPAPLI-------LPLGTYFFGY--------PYKAPSIEEDS------KKDPNL 309

  Fly   303 -SFHGTGFSMKKTRK 316
             .|.|.|.|::.:||
pombe   310 FKFEGAGTSLRASRK 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ufd1-like	NP_524023.1	UFD1	4..316	CDD:227469	122/338 (36%)
Ufd1-like	NP_524023.1	UFD1	17..190	CDD:281187	86/183 (47%)
ufd1	NP_596780.1	UFD1	1..341	CDD:227469	124/340 (36%)
ufd1	NP_596780.1	UFD1	32..208	CDD:281187	83/175 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	187	1.000	Domainoid score	I758
eggNOG	1	0.900	-	-		E1_COG5140
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H39090
Inparanoid	1	1.050	207	1.000	Inparanoid score	I969
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003822
OrthoInspector	1	1.000	-	-		oto100716
orthoMCL	1	0.900	-	-		OOG6_101567
Panther	1	1.100	-	-	LDO	PTHR12555
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2330
SonicParanoid	1	1.000	-	-		X2666
TreeFam	1	0.960	-	-
	13	12.850