DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mRpL2 and mrpl2

DIOPT Version :9

Sequence 1:	NP_524022.1	Gene:	mRpL2 / 39253	FlyBaseID:	FBgn0036135	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_001314714.1	Gene:	mrpl2 / 571648	ZFINID:	ZDB-GENE-050809-12	Length:	294	Species:	Danio rerio

Alignment Length:	225	Identity:	109/225 - (48%)
Similarity:	146/225 - (64%)	Gaps:	5/225 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 EKYTVEPLKITHLAGRDPVSGRLVAKGIGGGIKQQYRWVKWVR----DGPTEGAQEELVLEVLRD 114
            ||||:.|:.:....|||. :||:...|||||.||::|.:.:.|    .|..:....|.||||..|
Zfish    58 EKYTIRPIGMKKTGGRDH-TGRIKTHGIGGGHKQRHRIIDFQRLRSEPGKEQPVMVEKVLEVRYD 121

  Fly   115 GCRTAKVALVAVGDELKYILATENMKAGDILKTSRFIPRIPVRPNEGDAYPLGALPVGTRIHCLE 179
            .||:|.:||||.|:..::|:|::||:|||::::.|.|.|:.|...||||:|:|||||||.||.||
Zfish   122 PCRSADIALVAGGNRKRWIIASQNMEAGDLIQSCRGIGRMAVLAQEGDAHPVGALPVGTLIHNLE 186

  Fly   180 KNPGQMCHLIHAAGTFGTILRKFDEKVVVQLPSKREFAFQRTCMATVGRLSNPEHNKEHVGSAQR 244
            ..||:....|.||||.|.:|||.....::|||||.:.....||:|||||:||.:|||..:|.|..
Zfish   187 LFPGRGAQYIRAAGTCGVLLRKVSGTAIIQLPSKHQIQVLETCVATVGRVSNVDHNKRIIGKAGT 251

  Fly   245 MREMGNRPRSGLWKRKEGKHGRKIRRLPPM 274
            .|.:|.||.||.|:||.|..|||||.||.|
Zfish   252 NRWLGIRPSSGRWQRKGGWAGRKIRPLPAM 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mRpL2	NP_524022.1	Ribosomal_L2	68..147	CDD:278605	36/82 (44%)
mRpL2	NP_524022.1	Ribosomal_L2_C	161..275	CDD:281880	63/114 (55%)
mrpl2	NP_001314714.1	Ribosomal_L2_C	53..>260	CDD:332035	94/202 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586776
Domainoid	1	1.000	101	1.000	Domainoid score	I6944
eggNOG	1	0.900	-	-		E1_COG0090
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H69198
Inparanoid	1	1.050	200	1.000	Inparanoid score	I3744
OMA	1	1.010	-	-		QHG46120
OrthoDB	1	1.010	-	-		D1156335at2759
OrthoFinder	1	1.000	-	-		FOG0003807
OrthoInspector	1	1.000	-	-		oto40551
orthoMCL	1	0.900	-	-		OOG6_100234
Panther	1	1.100	-	-	LDO	PTHR13691
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1160
SonicParanoid	1	1.000	-	-		X3165
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800