DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mRpL2 and Mrpl2

DIOPT Version :9

Sequence 1:	NP_524022.1	Gene:	mRpL2 / 39253	FlyBaseID:	FBgn0036135	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_001365986.1	Gene:	Mrpl2 / 27398	MGIID:	1351622	Length:	315	Species:	Mus musculus

Alignment Length:	294	Identity:	125/294 - (42%)
Similarity:	163/294 - (55%)	Gaps:	32/294 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LLSTTLTIQTPFRTAPAFLQQLRGKTKVVEKPKPGAGQQFRRTVHFP-------------EKYTV 58
            |.|..:|.:.|.....|.:|     :.|:.:..|.......|.||..             .||||
Mouse    15 LASAAITARVPTLLPAAQIQ-----SNVLLQLPPALVSPSYRPVHMSADRSAKFVSWKSRTKYTV 74

  Fly    59 EPLKITHLAGRDPVSGRLVAKGIGGGIKQQYRWVKWVRDGPTEGAQ----EELVLEVLRDGCRTA 119
            :|:|:....|||. :||:...|||||.||.||.:.::|..|.:...    ||.|:.|..|.||:|
Mouse    75 KPVKMRKSGGRDH-TGRIRVHGIGGGHKQNYRMIDFLRFRPEKEKAPEPFEEKVVVVRYDPCRSA 138

  Fly   120 KVALVAVGDELKYILATENMKAGDILKTSRFIPRIPVRPNEGDAYPLGALPVGTRIHCLEKNPGQ 184
            .:||||.|...::|:|||||||||.:..|..|.|:.|...||||:|||||||||.|:.:|..||:
Mouse   139 DIALVAGGSRKRWIIATENMKAGDTILNSNHIGRMAVAAQEGDAHPLGALPVGTLINNVESEPGR 203

  Fly   185 MCHLIHAA---------GTFGTILRKFDEKVVVQLPSKREFAFQRTCMATVGRLSNPEHNKEHVG 240
            ....|.||         ||.|.:|||.:...::||||||:.....:|.|||||:||..||:..:|
Mouse   204 GAQYIRAAGGQAVSPSPGTCGVLLRKVNGTAIIQLPSKRQMQVLESCTATVGRVSNVNHNQRVIG 268

  Fly   241 SAQRMREMGNRPRSGLWKRKEGKHGRKIRRLPPM 274
            .|.|.|.:|.||.||||:||.|..|||||.||||
Mouse   269 KAGRNRWLGKRPNSGLWQRKGGWAGRKIRPLPPM 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mRpL2	NP_524022.1	Ribosomal_L2	68..147	CDD:278605	39/82 (48%)
mRpL2	NP_524022.1	Ribosomal_L2_C	161..275	CDD:281880	64/123 (52%)
Mrpl2	NP_001365986.1	RplB	75..>280	CDD:424298	92/205 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842357
Domainoid	1	1.000	101	1.000	Domainoid score	I6991
eggNOG	1	0.900	-	-		E1_COG0090
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H69198
Inparanoid	1	1.050	209	1.000	Inparanoid score	I3667
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46120
OrthoDB	1	1.010	-	-		D1156335at2759
OrthoFinder	1	1.000	-	-		FOG0003807
OrthoInspector	1	1.000	-	-		oto92936
orthoMCL	1	0.900	-	-		OOG6_100234
Panther	1	1.100	-	-	LDO	PTHR13691
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1160
SonicParanoid	1	1.000	-	-		X3165
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.800