Protein Alignment FoxK and FOXQ1

DIOPT Version :10

• Sequence 1: NP_001261701.1
• Gene: FoxK / 39252
• FlyBaseID: FBgn0036134
• Length: 760
• Species: Drosophila melanogaster
• Sequence 2: NP_150285.3
• Gene: FOXQ1 / 94234
• HGNCID: 20951
• Length: 403
• Species: Homo sapiens
• Alignment Length: 269
• Identity: 76/269 - (28%)
• Similarity: 115/269 - (42%)
• Gaps: 67/269 - (24%)

  Fly   365 APPAGAAAHLIAGD-------GPGIYSPLKISIPKKEQKSPYLSPTGTIS-AANSCPASPRQGFI 421
            :|.||..|....||       |||           .|:..|..:....:: .|.:..|.|..|
Human    50 SPAAGGGARDTQGDGEQSAGGGPG-----------AEEAIPAAAAAAVVAEGAEAGAAGPGAG-- 101

  Fly   422 QNQPNNYNNYGNNNTQDLFQTPSTASYNHNEKPPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKH 486
                      |..:.:.....|    |....||||||..||..||..:...:|||:.|..:::..
Human   102 ----------GAGSGEGARSKP----YTRRPKPPYSYIALIAMAIRDSAGGRLTLAEINEYLMGK 152

  Fly   487 YPYYRKETNKGWQNSIRHNLSLNRYFIKVARSQDEP-GKGSFWRIDPDSGAKLIDHSYKKRRQRS 550
            :|::| .:..||:||:|||||||..|:||.|....| ||.::|.::|:|.....|..:::||:|.
Human   153 FPFFR-GSYTGWRNSVRHNLSLNDCFVKVLRDPSRPWGKDNYWMLNPNSEYTFADGVFRRRRKRL 216

  Fly   551 SQ-------GFRPPY--GMPRSAPVSPSHMDNSRESSPLQDIVLQSAPGSPGM---SLEQRAADP 603
            |.       |.||..  |:|.:.|.:|                  :||.||.|   :.::..|.|
Human   217 SHRAPVPAPGLRPEEAPGLPAAPPPAP------------------AAPASPRMRSPARQEERASP 263

  Fly   604 EIIYNSQNA 612
            ...::|..|
Human   264 AGKFSSSFA 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA_FOXK	151..252	CDD:438740
		FH_FOXK	453..531	CDD:410800	35/78 (45%)
FOXQ1	NP_150285.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..75		9/35 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	94..116		6/37 (16%)
		FH_FOXQ1-like	119..197	CDD:410808	35/78 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	216..266		15/67 (22%)