DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxK and foxl2a

DIOPT Version :9

Sequence 1:	NP_001261701.1	Gene:	FoxK / 39252	FlyBaseID:	FBgn0036134	Length:	760	Species:	Drosophila melanogaster
Sequence 2:	NP_001038717.1	Gene:	foxl2a / 692279	ZFINID:	ZDB-GENE-060512-241	Length:	306	Species:	Danio rerio

Alignment Length:	247	Identity:	79/247 - (31%)
Similarity:	114/247 - (46%)	Gaps:	32/247 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   452 EKPPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKHYPYYRKETNKGWQNSIRHNLSLNRYFIKVA 516
            :||||||..||..||..:.:|:|||||||.:|:..:|:|.| ..||||||||||||||..||||.
Zfish    45 QKPPYSYVALIAMAIRESSEKRLTLSGIYQYIISKFPFYEK-NKKGWQNSIRHNLSLNECFIKVP 108

  Fly   517 RSQDEPGKGSFWRIDPDSGAKLIDHSYKKRRQRSSQGFRPP----------YGMPRSAPVSP--- 568
            |......||::|.:|| :...:.:....:||:|..:.||||          :|......:||
Zfish   109 REGGGERKGNYWTLDP-ACEDMFEKGNYRRRRRMKRPFRPPPTHFQPGKSLFGGEGYGYLSPPKY 172

  Fly   569 ---SHMDNSRESSPLQDIVLQSAPGSPGMSLEQRAADPEIIYNSQNAHQQQQQQQQQQQQQTLSN 630
               ..::||...:|:.....|.:.||.. .:..:.......||..:          :.|...|.:
Zfish   173 LQSGFINNSWSPAPMSYTSCQVSSGSVS-PVNMKGLSAPSSYNPYS----------RVQSIGLPS 226

  Fly   631 NSNQYSSGSPYYVTNQSSGVATP---QTHVEGSAASGGGGGGGVGALLALKR 679
            ..|.|:..|.::..:.:...|.|   |.....:||.....|.|.|...|..|
Zfish   227 MVNSYNGISHHHHHHHTHPHALPHAQQLSPATAAAPPVTTGNGTGLQFACSR 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017
FoxK	NP_001261701.1	Forkhead	453..540	CDD:278670	46/86 (53%)
foxl2a	NP_001038717.1	Forkhead	46..131	CDD:306709	46/86 (53%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820