Protein Alignment FoxK and Foxk2

DIOPT Version :9

• Sequence 1: NP_001261701.1
• Gene: FoxK / 39252
• FlyBaseID: FBgn0036134
• Length: 760
• Species: Drosophila melanogaster
• Sequence 2: XP_011247520.1
• Gene: Foxk2 / 68837
• MGIID: 1916087
• Length: 690
• Species: Mus musculus
• Alignment Length: 671
• Identity: 200/671 - (29%)
• Similarity: 262/671 - (39%)
• Gaps: 281/671 - (41%)

  Fly   151 SPPYG---------ELRFNQEVLPITDAVTVIGRNSSTSLVHFNVAENNLVSRKHFQVL------ 200
            |||.|         |..:..:...:|     ||||||...|..::..::.:||:|.::.
Mouse    24 SPPGGWAVARLEGREFEYLMKKRSVT-----IGRNSSQGSVDVSMGHSSFISRRHLEIFTPPGGG 83

  Fly   201 ------YDVELRA-----FFVQCLSKNGIFVDDFLQRRNVDPLRLPQ------------------ 236
                  ...:.|.     |:::||.|||:|||...|||...||:||:
Mouse    84 HSAAAPEPAQPRPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVVSICSPGCPGNCCVDHR 148

  Fly   237 ---------------------RCYFRFPSTEIRIEFESYVPATSSDAIDGHSPSLVVGGGGGVAG 280
                                 ||.||||||.|:|.|.:
Mouse   149 PCWPEIYRNLPASAFPEYWPSRCTFRFPSTNIKITFTA--------------------------- 186

  Fly   281 GGAHVIITPLPRDELHQQQLHHHQQQPHLQQQQHPHHPPAHHLPLQQQQQQQQPAHHPLPHTPHH 345
                                                      |..:::::|:.|.....|..||
Mouse   187 ------------------------------------------LSSEKREKQEAPESPVKPVQPH- 208

  Fly   346 PLHHTALHQQQQRSGSIVVAPPAGAAAHLIAGDGPGIYSPLKISIPKKEQK--SPYLSPTGTISA 408
                                                 .|||.|:||.....  ||..||||||||
Mouse   209 -------------------------------------ISPLTINIPDTMAHLISPLPSPTGTISA 236

  Fly   409 ANSCPASPR----QGF--------------IQNQPNNYNN-YGNNNTQDLFQTPSTASYNHNEKP 454
            |||||:|||    .|:              ..:||.|... .|.::.:|            :.||
Mouse   237 ANSCPSSPRGAGSSGYKVGRVMPSDLSLMADNSQPENEKEASGGDSPKD------------DSKP 289

  Fly   455 PYSYAQLIVQAISAAPDKQLTLSGIYSFIVKHYPYYRKETNKGWQNSIRHNLSLNRYFIKVARSQ 519
            ||||||||||||:.||||||||:|||:.|.|:||||| ..:||||||||||||||||||||.|||
Mouse   290 PYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYR-TADKGWQNSIRHNLSLNRYFIKVPRSQ 353

  Fly   520 DEPGKGSFWRIDPDSGAKLIDHSYKKRRQRSSQGFRPPYG--MPRSAPVSPSHM----------- 571
            :||||||||||||.|.:||::.:::|||.|....||.|.|  ..||||.||:|.
Mouse   354 EEPGKGSFWRIDPASESKLVEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHAGVLSAHSSGAQ 418

  Fly   572 ---DNSRESSP----------------LQDI-VLQSAPGSPGMSLEQRAADPEIIYNSQNAHQQQ 616
               ..|||.||                :|:. ..|||||||      .::.|.:|
Mouse   419 TPESLSREGSPAPLEPEPGASQPKLAVIQEARFAQSAPGSP------LSSQPVLI---------- 467

  Fly   617 QQQQQQQQQQTLSNNSNQYSSGSPYYVTNQSSGVATPQT-HVEGSAASGGGGGGGVGALLALKRN 680
                ..|:|...:.....|:..:|  ||..:|.....|| ||             |..:.|:...
Mouse   468 ----TVQRQLPPAIKPVTYTVATP--VTTPTSQPPVVQTVHV-------------VHQIPAVSVT 513

  Fly   681 HVMG-GGASQHTLHQQQAVAQ 700
            .|.| ..|:.:|:..|..|.|
Mouse   514 SVAGLAPANTYTVAGQAVVTQ 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017	38/138 (28%)
		Forkhead	453..540	CDD:278670	70/86 (81%)
Foxk2	XP_011247520.1	FHA	41..>124	CDD:238017	24/87 (28%)
		COG5025	<175..>381	CDD:227358	114/325 (35%)
		Forkhead	287..373	CDD:365978	69/86 (80%)
		PHA03247	<380..683	CDD:223021	49/190 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	147	1.000	Domainoid score	I4491
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	302	1.000	Inparanoid score	I2652
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	1	1.000	-	-		otm42535
orthoMCL	1	0.900	-	-		OOG6_104629
Panther	1	1.100	-	-	O	PTHR45881
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2114
SonicParanoid	1	1.000	-	-		X1668
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.860