DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxK and Foxl3

DIOPT Version :9

Sequence 1:	NP_001261701.1	Gene:	FoxK / 39252	FlyBaseID:	FBgn0036134	Length:	760	Species:	Drosophila melanogaster
Sequence 2:	XP_038945901.1	Gene:	Foxl3 / 680273	RGDID:	1594158	Length:	216	Species:	Rattus norvegicus

Alignment Length:	227	Identity:	68/227 - (29%)
Similarity:	101/227 - (44%)	Gaps:	55/227 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   428 YNNYGNNNTQDLFQTPSTASYNHNEKPPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKHYPYYRK 492
            ||.:  |:..|.:...|........:|.|||..||..||..:|..::||||||.||::.:||||
  Rat     9 YNCF--NDDADDYPAGSADEEKRLTRPAYSYIALIAMAIQQSPAGRVTLSGIYDFIMRKFPYYR- 70

  Fly   493 ETNKGWQNSIRHNLSLNRYFIKVARSQ-DEPGKGSFWRIDPDSGA--KLID----HSYKKRRQRS 550
            ...:.||||||||||||..|:||.|:: .:.|||::|..   :|.  .|:|    .::::||:|
  Rat    71 ANQRAWQNSIRHNLSLNSCFVKVPRTEGHDKGKGNYWTF---AGGCESLLDLFENGNFRRRRRR- 131

  Fly   551 SQGFRPPYGMPRSAPVSPSHMDNSRESSPLQDIVLQSAPGSPGMSLEQRAA-------------- 601
                |.|.......|:.|:               .:.:||..|.....|.|
  Rat   132 ----RGPKSEEAPGPLQPA---------------ARGSPGPDGTQAPDREAQARLVTHRDIKFSI 177

  Fly   602 -------DPEIIYNSQNAHQQQQQQQQQQQQQ 626
                   ||..:..| :.|.|:.:....:.||
  Rat   178 DYILSSPDPFPVLRS-SCHSQEARYPTLEPQQ 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017
FoxK	NP_001261701.1	Forkhead	453..540	CDD:278670	43/89 (48%)
Foxl3	XP_038945901.1	Forkhead	32..115	CDD:395192	42/86 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920