Protein Alignment FoxK and Foxm1

DIOPT Version :9

• Sequence 1: NP_001261701.1
• Gene: FoxK / 39252
• FlyBaseID: FBgn0036134
• Length: 760
• Species: Drosophila melanogaster
• Sequence 2: NP_113821.2
• Gene: Foxm1 / 58921
• RGDID: 61807
• Length: 771
• Species: Rattus norvegicus
• Alignment Length: 564
• Identity: 123/564 - (21%)
• Similarity: 196/564 - (34%)
• Gaps: 183/564 - (32%)

  Fly   304 QQQPHLQQQQHPHHPPAHHLPLQQQQQQ--------QQPA-----HHP-LPHTPHHPLHH----- 349
            |..|....::.....|....|.|.|..|        :.||     :|| :|:|....:.:
  Rat    21 QNAPSETSEEEAKRSPGQQEPTQAQASQDVAESSSCKFPAGIKIINHPTMPNTQVVAIPNNADIQ 85

  Fly   350 ---TALHQQQQRSGS-----IVVAPPAGAAAH------------------LIA---GDGPGIYSP 385
               |||..:.:.|||     .::....||::|                  ||.   |..||...
  Rat    86 SIITALTAKGKESGSSGPNKFILISSGGASSHPPDPQSQAQTSTDSKRTELITETLGPKPGAKG- 149

  Fly   386 LKISIPKKEQKSPYLSPTGTI--SAANSCPASPRQGFIQNQPNNYNNYGNNNTQDL--------- 439
              :.:||         |.|.:  ....||........:.|...|....|..::..|
  Rat   150 --VPVPK---------PPGALPRQRQESCGGEAAGCTLDNSLTNIQWLGKMSSDGLGRCSIKQEL 203

  Fly   440 --------------FQTPSTASYNH----NEKPPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKH 486
                          .:.||.||.:.    :|:|||||..:|..||::...|::||..||::|..|
  Rat   204 EEKENCHLEQNRVKVEAPSRASVSWQDSVSERPPYSYMAMIQFAINSTERKRMTLKDIYTWIEDH 268

  Fly   487 YPYYRKETNKGW------------QNSIRHNLSLNRYFIKVARSQDEPGKGSFWRIDPDSGAKL- 538
            :||::.....||            ||||||||||:..|:   |.....||.|||.|.|.:...|
  Rat   269 FPYFKHIAKPGWKCWHQAYHKLGPQNSIRHNLSLHDMFV---RETSANGKVSFWTIHPSANRYLT 330

  Fly   539 IDHSYKKRRQRSSQGFRPPYGMPRSAPVSPSHMDNSRESSPLQDIVLQSAPGSPGMSLEQRAADP 603
            :|           |.|:|   :...:|.||.|:::                       :|:..:|
  Rat   331 LD-----------QVFKP---LEPGSPQSPEHLES-----------------------QQKRPNP 358

  Fly   604 EIIYNSQNAHQQQQQQQQQQQQQTLSNNSNQYSSGSPYYVTNQSSGVATPQTHVEGSAASGGGGG 668
            |:..|.  ..:.:.....:::.:.|....:.|.....:.| |||. |..|...|....|:.
  Rat   359 ELRRNV--TIKTELPLGARRKMKPLLPRVSSYLVPIQFPV-NQSL-VLQPSVKVPLPLAAS---- 415

  Fly   669 GGVGALLALKRNHVMGGGASQHT---------LHQQQAVAQQQHSEIIYEELPTDYSG-----HI 719
                         :|....::|:         |...:.:|....:|.:.||.|....|     .|
  Rat   416 -------------LMSSELARHSKRVRIAPKVLLSNEGIAPLPATEPMKEEKPLLGEGLLPLLPI 467

  Fly   720 EASEEECVTTATDATVAKRP-KYVSEVLX-----CVRIQKHRQN 757
            ::.:||.:....|....:|| |..|..|.     |..:::...|
  Rat   468 QSIKEEVIQPGEDIPHLERPIKVESPPLEEWPSPCASVKEELSN 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017
		Forkhead	453..540	CDD:278670	39/99 (39%)
Foxm1	NP_113821.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..54		7/32 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	94..165		15/82 (18%)
		FH	235..322	CDD:238016	36/89 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	340..361		7/43 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	542..568
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	584..655
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	693..718

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820