DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxK and foxe1

DIOPT Version :9

Sequence 1:	NP_001261701.1	Gene:	FoxK / 39252	FlyBaseID:	FBgn0036134	Length:	760	Species:	Drosophila melanogaster
Sequence 2:	XP_005159967.1	Gene:	foxe1 / 567676	ZFINID:	ZDB-GENE-061116-1	Length:	354	Species:	Danio rerio

Alignment Length:	299	Identity:	90/299 - (30%)
Similarity:	132/299 - (44%)	Gaps:	47/299 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   390 IPKKEQKSPYLSPTGTISAANSCPASPRQGFIQNQPNNYNNYGNNNTQDLFQTPSTASYNHNEKP 454
            :.|.|..||  |.| |:...:|..|.|::|..:.:|                       ....||
Zfish     3 VVKVESDSP--SET-TLPVNDSQRAEPQRGRRRKRP-----------------------LQRGKP 41

  Fly   455 PYSYAQLIVQAISAAPDKQLTLSGIYSFIVKHYPYYRKETNKGWQNSIRHNLSLNRYFIKVARSQ 519
            ||||..||..||:.:||::|||.|||.||.:.:|:|| :.:|.|||||||||:||..|||:.|..
Zfish    42 PYSYIALISMAIANSPDRKLTLGGIYKFITERFPFYR-DNSKKWQNSIRHNLTLNDCFIKIPREP 105

  Fly   520 DEPGKGSFWRIDPDSGAKLIDHSYKKRRQRSSQG-FRPPYGMPRSAPV-SPSHMDNSRESSPLQD 582
            ..||||::|.:||::.......|:.:||:|..:. |.........:|| ||..:..|..::.:..
Zfish   106 GRPGKGNYWALDPNAEDMFESGSFLRRRKRFKRSDFTTYSSYVHESPVFSPVQIARSAYANSVYS 170

  Fly   583 IVLQSAP------------GSPGMSLEQ-RAADPEIIYNSQNAHQQQQQQQQQQQQQTLSNNSNQ 634
            .:..|.|            .||..:..| |......:..|.:...|..:...||..::.|..|..
Zfish   171 NMAVSPPYAQQLPSAYYQSSSPNFTAGQSRVFRINSLIGSPSRMGQNAEMIPQQSCRSFSPESGS 235

  Fly   635 YSSGSPYYVTNQSSGVATPQTHVEGS-----AASGGGGG 668
            .|.|.|.:.....:|......:...|     |.||.|.|
Zfish   236 CSLGGPGFQHQSCNGETVLSCYSSSSNNMAFAYSGPGHG 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017
FoxK	NP_001261701.1	Forkhead	453..540	CDD:278670	46/86 (53%)
foxe1	XP_005159967.1	FH	40..128	CDD:214627	46/88 (52%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820