DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxK and foxj2

DIOPT Version :9

Sequence 1:	NP_001261701.1	Gene:	FoxK / 39252	FlyBaseID:	FBgn0036134	Length:	760	Species:	Drosophila melanogaster
Sequence 2:	XP_686801.4	Gene:	foxj2 / 558490	ZFINID:	ZDB-GENE-100922-240	Length:	516	Species:	Danio rerio

Alignment Length:	244	Identity:	73/244 - (29%)
Similarity:	104/244 - (42%)	Gaps:	77/244 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   449 NHNEKPPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKHYPYYRKETNKGWQNSIRHNLSLNRYFI 513
            |...|||:|||.||..|||:||:.:|:|:.||::|...:|||.: ..:||:||||||||||:.|.
Zfish    53 NSKVKPPHSYATLIAMAISSAPEMKLSLNDIYTWISDTFPYYCR-AGRGWKNSIRHNLSLNKCFR 116

  Fly   514 KVARSQDEPGKGSFWRID--PDSGAKLIDHSYKKRRQRSSQGFRPPY-----------------G 559
            ||.|.|.:|||||:|.:|  |:|              ...:|.:.||                 .
Zfish   117 KVPRPQSDPGKGSYWTMDVPPES--------------TQPRGVKRPYTDDEHVVTPFPETQLPAN 167

  Fly   560 MPRSAPVSPSHMD-------NSRESSPLQDIVLQSAPGSPGMSLEQRAADPEI-----------I 606
            .|...|..|....       ..|.:.|    |..|.|.:|       .|||.:           :
Zfish   168 QPEPLPPQPDTKSTFPPPPCKQRPAIP----VPSSLPSNP-------HADPPLRFSFADLNLPDL 221

  Fly   607 YNSQNA--HQQQQQQQQQQQQQTLSNNSNQYSSGSPYYVTNQSSGVATP 653
            |||..:  ...:::...|....||..            :|:.|:.:.||
Zfish   222 YNSFQSLCRSMREKVTSQSDVSTLLG------------LTHDSTPLHTP 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017
FoxK	NP_001261701.1	Forkhead	453..540	CDD:278670	47/88 (53%)
foxj2	XP_686801.4	Forkhead	57..134	CDD:278670	44/77 (57%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820