DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxK and Foxj2

DIOPT Version :9

Sequence 1:	NP_001261701.1	Gene:	FoxK / 39252	FlyBaseID:	FBgn0036134	Length:	760	Species:	Drosophila melanogaster
Sequence 2:	XP_006237373.1	Gene:	Foxj2 / 502886	RGDID:	1565101	Length:	623	Species:	Rattus norvegicus

Alignment Length:	456	Identity:	122/456 - (26%)
Similarity:	169/456 - (37%)	Gaps:	160/456 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   386 LKISIPKKEQKSPYLSPTGTISAANSCPASPRQGFIQNQPNNYNNYGNNNTQDLFQTPSTASYNH 450
            |:.:|.|....|....|.||...:...|..|.....:::                     ||.:.
  Rat    60 LRATIEKLGSASQAGPPGGTRKCSPGSPTDPNATLSKDE---------------------ASVHQ 103

  Fly   451 NEKPPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKHYPYYRKETNKGWQNSIRHNLSLNRYFIKV 515
            :.||.||||.||..||:::|.|::|||.||.:|..::||| |....||:||||||||||:.|.||
  Rat   104 DGKPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYY-KNAGIGWKNSIRHNLSLNKCFRKV 167

  Fly   516 ARSQDEPGKGSFWRID--PDSGAK--------LIDHSYKKRRQRSSQGFRPPYGMPRSAPVSPSH 570
            .|.:|:|||||:|.||  ||...|        |...|.::...:|.:|     |:|.|...|.||
  Rat   168 PRPRDDPGKGSYWTIDTCPDISRKRRHPPDDDLSQDSPEQEASKSPRG-----GVPGSGEASLSH 227

  Fly   571 MDNSRESSPLQDIVLQS-------------------APGSPGM---------------------- 594
            ..|.:.|       |||                   |.|:||.
  Rat   228 EGNPQMS-------LQSPSSMASYSQGPGPVDGGAVAAGAPGQESTEGAPPLYNTNHDFKFSYSE 285

  Fly   595 ---------------SLEQRAADPE----------------IIYNSQNAHQQQQQQQQQQQQQTL 628
                           |:.:|::..:                .:|..|...|||||||||||||..
  Rat   286 INFQDLSWSFRNLYKSMLERSSSSQHGFSSLLGDMPPSNNYYMYQQQQQQQQQQQQQQQQQQQQQ 350

  Fly   629 SNN-------------------------SNQYSSGSPYYVTNQSSGVATPQTHVEGSAASGGGGG 668
            ...                         ||  ..|:|...|....|..||.....|:...|...|
  Rat   351 QQQQPPPQPQPPPQQPQPQQQQAPTQGPSN--VGGAPPLHTPSPDGCTTPGGKQAGAEVYGPPTG 413

  Fly   669 GGVGALLALKRNHVMGGGASQHTLH----------QQQAVAQQQHSEIIYEELPTDYSGHIEASE 723
                  :|:....:..||...|..|          ||||.:|...:...: ..|.|:..:|::.:
  Rat   414 ------MAMHPPPLQHGGYHPHQHHPHSHPAQQPPQQQAQSQAPINSTGF-AFPPDWCSNIDSLK 471

  Fly   724 E 724
            |
  Rat   472 E 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017
FoxK	NP_001261701.1	Forkhead	453..540	CDD:278670	51/96 (53%)
Foxj2	XP_006237373.1	Forkhead	106..183	CDD:278670	45/77 (58%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820