DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxK and fd102C

DIOPT Version :9

Sequence 1:	NP_001261701.1	Gene:	FoxK / 39252	FlyBaseID:	FBgn0036134	Length:	760	Species:	Drosophila melanogaster
Sequence 2:	NP_651951.1	Gene:	fd102C / 43843	FlyBaseID:	FBgn0039937	Length:	599	Species:	Drosophila melanogaster

Alignment Length:	411	Identity:	106/411 - (25%)
Similarity:	153/411 - (37%)	Gaps:	121/411 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   326 QQQQQQQQPAHHPLPHTPH-HPLHHTALHQQQQRSGSI----------------VVAPPAGAAAH 373
            |.|....:.::.|.|..|: :||..|...|.|..:.::                :..|..|...
  Fly    16 QDQGTSSRDSNVPKPSLPNIYPLGTTRTSQAQSTTMTLEQYRLQLYNYALNIERLRCPQYGGTG- 79

  Fly   374 LIAGDGPGIYSPLKISIPKKEQKSPYLSPTGTISAANSCPASPRQGFIQNQPNNYNNYGNNNTQD 438
                 |.|..:|.....|.....|..|.....::|.::....|:                  ||.
  Fly    80 -----GSGASAPWLHLSPYGHHGSGSLPSVNRMAALSTISLFPQ------------------TQR 121

  Fly   439 LFQTPSTASYNHNEKPPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKHYPYYRKETNKGWQNSIR 503
            :||.       ...||.:||..||..||.::.|.:|.||.||.:|:.:|||:|.. ..||:||||
  Fly   122 IFQP-------EEPKPQHSYIGLIAMAILSSTDMKLVLSDIYQYILDNYPYFRSR-GPGWRNSIR 178

  Fly   504 HNLSLNRYFIKVARSQDEPGKGSFWRIDPDSGAKLIDHSYKK---RRQRSSQGFRPPYGM----- 560
            ||||||..|||..||.:  |||.:|.|.|   |.:.|  ::|   ||:::.:..|...|:
  Fly   179 HNLSLNDCFIKSGRSAN--GKGHYWAIHP---ANMED--FRKGDFRRRKAQRKVRKHMGLSVDDA 236

  Fly   561 PRSAPVSPSHMDNSRESSPLQDIVLQ-SAPG----------------SPGMSLEQRAADPEIIYN 608
            ...:| ||..:|.:....|.....|| ||.|                :|||: .....||.::..
  Fly   237 STDSP-SPPPLDLTTPPPPSSQSALQLSALGYPYHQHYIGQFFNRSSAPGMT-HYSPPDPALLMQ 299

  Fly   609 SQNAHQQQQQQQQQQQQQ-----------------TLSNNSNQ---------------------Y 635
            .|.|:...|..|..|.||                 |::|..:|                     .
  Fly   300 RQEANNLDQTIQPTQLQQPHSHHQHFAYINSTTTTTIANMFSQTRKRQFDVASLLAPDVQIVDIV 364

  Fly   636 SSGSPYYVTNQSSGVATPQTH 656
            |......||..:|...|.|||
  Fly   365 SEDQESSVTPTTSARTTTQTH 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017
FoxK	NP_001261701.1	Forkhead	453..540	CDD:278670	43/86 (50%)
fd102C	NP_651951.1	Forkhead	129..213	CDD:278670	44/91 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445541
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2114
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.780