DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxK and foxg1b

DIOPT Version :9

Sequence 1:	NP_001261701.1	Gene:	FoxK / 39252	FlyBaseID:	FBgn0036134	Length:	760	Species:	Drosophila melanogaster
Sequence 2:	NP_998079.2	Gene:	foxg1b / 405850	ZFINID:	ZDB-GENE-040426-2437	Length:	341	Species:	Danio rerio

Alignment Length:	300	Identity:	97/300 - (32%)
Similarity:	135/300 - (45%)	Gaps:	58/300 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   437 QDLFQTPSTASYNHN-----------------EKPPYSYAQLIVQAISAAPDKQLTLSGIYSFIV 484
            |||.:.|..|..::.                 :|||:||..||:.||..:|:|:|||:|||.||:
Zfish    44 QDLDKPPEDAEMDNAQRDAEEPELQTKKGKKFDKPPFSYNALIMMAIRQSPEKRLTLNGIYEFIM 108

  Fly   485 KHYPYYRKETNKGWQNSIRHNLSLNRYFIKVARSQDEPGKGSFWRIDPDSGAKLIDHSYKKRRQR 549
            |::|||| |..:|||||||||||||:.|:||.|..|:||||::|.:||.|....|..:..|.|:|
Zfish   109 KNFPYYR-EHKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDPSSDDVFIGGTTGKLRRR 172

  Fly   550 SSQGFRPPYGMPRSAPVSPSHMD-NSRESSPLQDIVLQSAP----------GSPGMSLEQRAADP 603
            |:.. |....|.|....:|..:. ..|.|:||   ..|.:|          ||....|.|.....
Zfish   173 SATS-RGKLVMKRGLRFAPLGLGLGERPSNPL---YWQLSPFLPLHHSHYNGSAHGFLNQGHTYG 233

  Fly   604 EIIYNSQNAHQQQQQQQQQQQQQTLSNNSNQYSSGSP----------YYVTNQSSGVATPQTHVE 658
            .::...:........:|.........|.||.|....|          |:|    .|...||:.
Zfish   234 TLLPGVEPLGNGDMSRQILGASSGSINLSNGYGVSPPAAGLLSGHNGYFV----PGAQQPQSL-- 292

  Fly   659 GSAASGGGGGGGVGALL--ALK------RNHVMGGGASQH 690
             .:|.|.|.......||  :|:      .:.:.||..|||
Zfish   293 -PSAPGYGISSSQSPLLSDSLRTSLPSFTSPLSGGLLSQH 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017
FoxK	NP_001261701.1	Forkhead	453..540	CDD:278670	51/86 (59%)
foxg1b	NP_998079.2	FH	77..165	CDD:214627	52/88 (59%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820