DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxK and foxd1

DIOPT Version :9

Sequence 1:	NP_001261701.1	Gene:	FoxK / 39252	FlyBaseID:	FBgn0036134	Length:	760	Species:	Drosophila melanogaster
Sequence 2:	NP_998078.2	Gene:	foxd1 / 405849	ZFINID:	ZDB-GENE-040426-2094	Length:	343	Species:	Danio rerio

Alignment Length:	201	Identity:	72/201 - (35%)
Similarity:	91/201 - (45%)	Gaps:	55/201 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   446 ASYNHNEKPPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKHYPYYRKETNKGWQNSIRHNLSLNR 510
            ||.|...||||||..||..||..:|.|:||||.|..||...:|||| |....||||||||||||.
Zfish    67 ASKNTLVKPPYSYIALITMAILQSPKKRLTLSEICDFISNRFPYYR-EKFPAWQNSIRHNLSLND 130

  Fly   511 YFIKVARSQDEPGKGSFWRIDPDSGAKLIDHSYKKRRQRSSQ-----------GFRP-------- 556
            .|:|:.|....||||::|.:||:|.....:.|:.:||:|..:           ||.|
Zfish   131 CFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKRQQAPELLREHGGFLPSAAAYGYG 195

  Fly   557 PYGMPRSAPVSPSHMDNSRESSPLQDIVLQSAPGSPGMSLEQRAADPEIIYNSQNAHQQQQQQQQ 621
            |||.                              ..|:.|:...|...::     |.|||||||.
Zfish   196 PYGC------------------------------GYGLQLQSYHAHSALL-----AFQQQQQQQP 225

  Fly   622 QQQQQT 627
            ...:.|
Zfish   226 PPSRNT 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017
FoxK	NP_001261701.1	Forkhead	453..540	CDD:278670	47/86 (55%)
foxd1	NP_998078.2	Forkhead	74..160	CDD:278670	47/86 (55%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820