DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxK and foxq1b

DIOPT Version :9

Sequence 1:	NP_001261701.1	Gene:	FoxK / 39252	FlyBaseID:	FBgn0036134	Length:	760	Species:	Drosophila melanogaster
Sequence 2:	NP_998072.1	Gene:	foxq1b / 405843	ZFINID:	ZDB-GENE-040426-2090	Length:	283	Species:	Danio rerio

Alignment Length:	237	Identity:	69/237 - (29%)
Similarity:	103/237 - (43%)	Gaps:	33/237 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   448 YNHNEKPPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKHYPYYRKETNKGWQNSIRHNLSLNRYF 512
            |....||||||..||..||..:...:|||:.|..:::|.:|::| .:..||:||:|||||||..|
Zfish    40 YTRRPKPPYSYIALIAMAIRDSNTGRLTLAEINEYLMKKFPFFR-GSYTGWRNSVRHNLSLNDCF 103

  Fly   513 IKVARSQDEP-GKGSFWRIDPDSGAKLIDHSYKKRRQRSSQGFRPPYGMPRSAPVSPSHMDNSRE 576
            :||.|....| ||.::|.::|.|.....|..:::||:|.|:........|...|...|.:....|
Zfish   104 LKVLRDPSRPWGKDNYWMLNPHSEYTFADGVFRRRRKRISKKILGSAESPERVPADDSRLPARDE 168

  Fly   577 SSP--LQDIVLQSAPGSPGMSLEQRAAD-------------PEIIYNSQNAHQQQQQQQQQQQQQ 626
            |..  .....:.|....|.|..||...|             |..:..:.....|.:.|.
Zfish   169 SVSKFSSSFAIDSILSKPFMRREQSTDDTCFGTTRLMMSAAPHFLPVAMGFPPQSRFQV------ 227

  Fly   627 TLSNNSNQYSSGSPYYVTNQS-----SGVATPQTHVEGSAAS 663
                 |::.|:..|.|..|.:     |.:|..|:.:.|.|.|
Zfish   228 -----SSEVSNVFPIYRCNTADISNISRMADIQSSLPGLAHS 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017
FoxK	NP_001261701.1	Forkhead	453..540	CDD:278670	38/87 (44%)
foxq1b	NP_998072.1	FH	45..134	CDD:214627	39/89 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920