DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment FoxK and foxi4.2

DIOPT Version :9

Sequence 1:NP_001261701.1 Gene:FoxK / 39252 FlyBaseID:FBgn0036134 Length:760 Species:Drosophila melanogaster
Sequence 2:NP_989265.1 Gene:foxi4.2 / 394878 XenbaseID:XB-GENE-487658 Length:363 Species:Xenopus tropicalis


Alignment Length:387 Identity:103/387 - (26%)
Similarity:175/387 - (45%) Gaps:94/387 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   324 PLQQQQQQQQPAHHPLPH------TPHHPLH-------HTALHQQQQRSGSIVVAPPAGAAAHLI 375
            |:||..||:.|| ..|||      .|...|:       ..:||..|:.....:....:.|..:|.
 Frog     3 PVQQPAQQRSPA-SSLPHPKRAQEAPDMALYCDNFMYPQQSLHPSQRGPNFAIGEYTSPANPYLW 66

  Fly   376 AGDGPGI-----YSPLKISIPKKEQKSPYLSPTGTISAANSCPASPRQGFIQNQPNNYNNYGNNN 435
            .| |.|:     |||         ..:||:.|:.         .:|::.|:.|.|    .:|...
 Frog    67 LG-GHGVNNAPNYSP---------SPAPYMPPSF---------GAPQRQFLPNSP----AFGGTE 108

  Fly   436 TQDLFQTPSTASYNHNEK---PPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKHYPYYRKETNKG 497
            ...:    |.||.....|   |||||:.||..||..|.|::||||.||.::.:::|:|:| :..|
 Frog   109 LSWM----SAASQEELLKMVRPPYSYSALIAMAIQHASDRRLTLSQIYQYVAENFPFYKK-SKAG 168

  Fly   498 WQNSIRHNLSLNRYFIKVARSQDEPGKGSFWRIDPDSGAKLIDH-SYKKRRQRSSQGFRPPYGMP 561
            ||||||||||||..|.||.|.:::||||::|.:||:. .|:.|: :::::|:..|..     ...
 Frog   169 WQNSIRHNLSLNDCFKKVPRDENDPGKGNYWTLDPNC-EKMFDNGNFRRKRKPKSDA-----NSA 227

  Fly   562 RSAPVSPSHMD-NSRESSPLQDIVLQSAPGSPGMSLEQRAADPEII---------------YNSQ 610
            :.|.:...|:: ..:||.|:   :..|:|..|..:...::..|..:               .::.
 Frog   228 KIAKIGEDHLNPKGKESPPM---ITPSSPEEPSPTGHSKSPSPPAVTYTPCLTNFIGSMTAVDAA 289

  Fly   611 NAHQQQQ----QQQQQQQQQTLSN--------------NSNQYSSGSPYYVTNQSSGVATPQ 654
            .|::|..    .:..|:...:||:              :::.:.:.||||.:..::....||
 Frog   290 TANRQGPLGLLNELSQRNISSLSSFISGSAVDQSAEHPDTSLFYNRSPYYSSFPTTAQKQPQ 351

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FoxKNP_001261701.1 FHA <170..253 CDD:238017
Forkhead 453..540 CDD:278670 46/89 (52%)
foxi4.2NP_989265.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..24 10/21 (48%)
Forkhead 125..210 CDD:306709 45/86 (52%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 210..269 12/66 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 344..363 2/8 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1270467at2759
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2114
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.950

Return to query results.
Submit another query.