DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxK and foxi1

DIOPT Version :9

Sequence 1:	NP_001261701.1	Gene:	FoxK / 39252	FlyBaseID:	FBgn0036134	Length:	760	Species:	Drosophila melanogaster
Sequence 2:	NP_988949.1	Gene:	foxi1 / 394546	XenbaseID:	XB-GENE-494125	Length:	373	Species:	Xenopus tropicalis

Alignment Length:	340	Identity:	103/340 - (30%)
Similarity:	153/340 - (45%)	Gaps:	68/340 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   335 AHHPLPHTPHHP---------------LHHTALHQQQQRSGSIVVAPPAGAAAHLIAGDGPGIYS 384
            ||.|....|..|               :.|.......||..:...|..:..|...:..:||.|..
Frog     8 AHSPPRCGPQFPSIGQEPPEMNIYCDSIFHPQTMPSPQRPSNFETADYSTTANPYLWLNGPSITP 72

  Fly   385 PLKISIPKKEQKSPYLSPTGTISAANSCPASPRQGFIQNQ--PNNYNNYGNNNTQDL--FQTPST 445
            |            |||      ..:|:....|:...:|.|  ||.:...|:    ||  ...||.
Frog    73 P------------PYL------PGSNTSHFMPQSYGMQRQLLPNMHGLGGS----DLGWLPIPSQ 115

  Fly   446 ASYNHNEKPPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKHYPYYRKETNKGWQNSIRHNLSLNR 510
            .......:|||||:.||..||..||||:||||.||.::..::|:|.| :..|||||||||||||.
Frog   116 EELMKLVRPPYSYSALIAMAIHGAPDKRLTLSQIYQYVADNFPFYNK-SKAGWQNSIRHNLSLND 179

  Fly   511 YFIKVARSQDEPGKGSFWRIDPDSGAKLIDH-SYKKRRQRSSQGFRPPYGMPRSAPVSPSHMDNS 574
            .|.||.|.:|:||||::|.:||:. .|:.|: :::::|:|.|.  ..|.|...|.....|.::.|
Frog   180 CFKKVPRDEDDPGKGNYWTLDPNC-EKMFDNGNFRRKRKRKSD--VSPNGQISSDKPEGSPLNES 241

  Fly   575 RESSPLQDIVLQSAPGSPGMSLEQRAADPEI------IYNSQNAHQQQQQQQQQQQQQTLSNNSN 633
            .::....|::..|:||:...| |:|:..|.|      ..:|..|:               .|::|
Frog   242 PKNGEHHDMLGNSSPGTDDSS-EKRSPPPSITPCLNNFLSSMTAY---------------VNSAN 290

  Fly   634 QYSSGSPYYVTNQSS 648
            ..|...|..:||:.|
Frog   291 PVSRSVPLGLTNEPS 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017
FoxK	NP_001261701.1	Forkhead	453..540	CDD:278670	48/86 (56%)
foxi1	NP_988949.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..23		5/14 (36%)
		Forkhead	123..208	CDD:365978	48/86 (56%)
		COG5025	124..>308	CDD:227358	75/202 (37%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	208..274		18/68 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920