DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxK and foxi3b

DIOPT Version :9

Sequence 1:	NP_001261701.1	Gene:	FoxK / 39252	FlyBaseID:	FBgn0036134	Length:	760	Species:	Drosophila melanogaster
Sequence 2:	NP_944600.1	Gene:	foxi3b / 387258	ZFINID:	ZDB-GENE-031126-4	Length:	383	Species:	Danio rerio

Alignment Length:	299	Identity:	87/299 - (29%)
Similarity:	131/299 - (43%)	Gaps:	73/299 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   304 QQQPHLQQQQHPHHPPAHHLPLQQQQQQQQPAHHPLPHTPHHPLHHTALHQQQQRSGSIVVAPPA 368
            |:.|.|......::||    |.....|:..|:.:.|                    |....:.|
Zfish    23 QEPPELSLYSDSYYPP----PSLPSPQRTNPSSYEL--------------------GDYAASSP- 62

  Fly   369 GAAAHLIAGDGPGIYSPLKISIPKKEQKSPYLSPTGTISAANSCPASPRQGFIQNQPNNYNNY-- 431
               ...:..:.||:.|            :|||..|       ..||.|  .|:   |.:|...
Zfish    63 ---NPYLWFNSPGMNS------------APYLGGT-------PGPAGP--SFV---PQHYGMQRP 100

  Fly   432 --------GNNNTQDLFQTPSTASYNHNEKPPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKHYP 488
                    |.......|..||........:|||||:.||..||..||:::||||.||.::..::|
Zfish   101 YLGPGPPGGPGGELSWFSMPSQEDLMKLVRPPYSYSALIAMAIHGAPERRLTLSQIYQYVADNFP 165

  Fly   489 YYRKETNKGWQNSIRHNLSLNRYFIKVARSQDEPGKGSFWRIDPDSGAKLIDH-SYKKRRQRSSQ 552
            :|.| :..|||||||||||||..|.||.|.:|:||||::|.:||:. .|:.|: :::::|:|.|.
Zfish   166 FYNK-SKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNC-EKMFDNGNFRRKRKRKSD 228

  Fly   553 GFRPPYGMPR--SAPVSPSHMDNSRESSPLQDIVLQSAP 589
                  .:|.  |:..:.|...|.|.|...|.|.:.::|
Zfish   229 ------SLPEKSSSGGNESGDSNGRGSPKSQSIDISTSP 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017
FoxK	NP_001261701.1	Forkhead	453..540	CDD:278670	46/86 (53%)
foxi3b	NP_944600.1	FH	130..218	CDD:214627	47/89 (53%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820