DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxK and foxi1

DIOPT Version :9

Sequence 1:	NP_001261701.1	Gene:	FoxK / 39252	FlyBaseID:	FBgn0036134	Length:	760	Species:	Drosophila melanogaster
Sequence 2:	NP_859424.1	Gene:	foxi1 / 353313	ZFINID:	ZDB-GENE-030505-1	Length:	377	Species:	Danio rerio

Alignment Length:	419	Identity:	122/419 - (29%)
Similarity:	171/419 - (40%)	Gaps:	144/419 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   305 QQPHLQQQQHPHHPPAHHLPLQQQ-------------QQQQQPAHHPLPHTPHHPLHHTALHQQQ 356
            |||..||..          |||||             ...||..||      ||..||   ||:
Zfish    14 QQPSSQQTS----------PLQQQDILDMTVYCDSNFSMYQQNLHH------HHHHHH---HQR- 58

  Fly   357 QRSGSIVVAPPAGAAAHLIAGDGPGIYSPLKISIPKKEQKSPYL---SPTGTISAANSCP--ASP 416
                     |||..:::     |.|.||        ....:|||   ||     ...|.|  :||
Zfish    59 ---------PPAHPSSY-----GLGEYS--------SPSTNPYLWMNSP-----GITSTPYLSSP 96

  Fly   417 RQG-FIQNQPNNYNNYGNNNTQDLFQTPSTA---------SYNHNE------KPPYSYAQLIVQA 465
            ..| :||      :.:|:|..|  |..|.|.         |.:..:      :|||||:.||..|
Zfish    97 NGGSYIQ------SGFGSNQRQ--FLPPPTGFGSADLGWLSISSQQELFKMVRPPYSYSALIAMA 153

  Fly   466 ISAAPDKQLTLSGIYSFIVKHYPYYRKETNKGWQNSIRHNLSLNRYFIKVARSQDEPGKGSFWRI 530
            |..|.||:||||.||.::..::|:|:| :..|||||||||||||..|.||||.:|:||||::|.:
Zfish   154 IQNAQDKKLTLSQIYQYVADNFPFYKK-SKAGWQNSIRHNLSLNDCFKKVARDEDDPGKGNYWTL 217

  Fly   531 DPDSGAKLIDH-SYKKRRQRSSQG----------------------------FRPPYGMPRSAPV 566
            ||:. .|:.|: :::::|:|.:.|                            ..|....|:|:|
Zfish   218 DPNC-EKMFDNGNFRRKRKRRADGNAMSVKSEDALKLADTSSLMSASQPSLQNSPTSSDPKSSP- 280

  Fly   567 SPSHMDNSRESSP------------LQDIVLQSAPGSP---GMSLEQRAADPEIIYNSQNAHQQQ 616
            ||     |.|.||            :....::|..||.   |...:...:..||...|:..|...
Zfish   281 SP-----SAEHSPCFSNFIGNMNSIMSGNAVRSRDGSSAHLGDFTQHGMSGHEISPPSEPGHLNT 340

  Fly   617 QQQQQQQQQQTLSNNSNQYSSGSPYYVTN 645
            .:........   |||...:|.|.::..|
Zfish   341 NRLNYYSASH---NNSGLINSISNHFSVN 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017
FoxK	NP_001261701.1	Forkhead	453..540	CDD:278670	48/86 (56%)
foxi1	NP_859424.1	Forkhead	141..227	CDD:278670	48/87 (55%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920