DRSC/TRiP Functional Genomics Resources

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Protein Alignment FoxK and FOXI3

DIOPT Version :9

Sequence 1:NP_001261701.1 Gene:FoxK / 39252 FlyBaseID:FBgn0036134 Length:760 Species:Drosophila melanogaster
Sequence 2:NP_001129121.1 Gene:FOXI3 / 344167 HGNCID:35123 Length:420 Species:Homo sapiens


Alignment Length:370 Identity:98/370 - (26%)
Similarity:151/370 - (40%) Gaps:97/370 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   365 APPAGAAAHLIAGDGPGIYSPLKISI--------------PKKEQKSPYLSP---TGTISA---- 408
            ||||.||...:..:|||:..|...:.              |......|:|.|   .||...    
Human    44 APPAAAANPYLWLNGPGVGGPPSAAAAAAAAYLGAPPPPPPPGAAAGPFLQPPPAAGTFGCSQRP 108

  Fly   409 -ANSCPASPRQGFIQNQPNNYNNYGNNNTQDLFQTPSTASYNHNEKPPYSYAQLIVQAISAAPDK 472
             |...||:|........|.........:.:||.:.         .:|||||:.||..||.:||::
Human   109 FAQPAPAAPASPAAPAGPGELGWLSMASREDLMKM---------VRPPYSYSALIAMAIQSAPER 164

  Fly   473 QLTLSGIYSFIVKHYPYYRKETNKGWQNSIRHNLSLNRYFIKVARSQDEPGKGSFWRIDPDSGAK 537
            :||||.||.|:...:|:|:: :..|||||||||||||..|.||.|.:|:||||::|.:||:. .|
Human   165 KLTLSHIYQFVADSFPFYQR-SKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNC-EK 227

  Fly   538 LIDH-SYKKRRQRSSQ--------------------------GFRPPYGMPRSAPVSPSHMDNSR 575
            :.|: :::::|:|.|:                          |.:|....| |..:.|||.....
Human   228 MFDNGNFRRKRKRRSEASNGSTVAAGTSKSEEGLSSGLGSGVGGKPEEESP-STLLRPSHSPEPP 291

  Fly   576 ESSPLQDIVLQSAPGSP----------------GMSLEQRAADPEIIYNSQNAHQQQQQQQQQ-- 622
            |.:.    ...|:||.|                .:|:....:....:..|::...|..|....  
Human   292 EGTK----STASSPGGPMLTSTPCLNTFFSSLSSLSVSSSVSTQRALPGSRHLGIQGAQLPSSGV 352

  Fly   623 --------------QQQQTLSNNSNQYSSGSPYYVTNQSSGVATP 653
                          |...:.||::.|.||....:..:.|.|.::|
Human   353 FSPTSISEASADTLQLSNSTSNSTGQRSSYYSPFPASTSGGQSSP 397

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FoxKNP_001261701.1 FHA <170..253 CDD:238017
Forkhead 453..540 CDD:278670 46/86 (53%)
FOXI3NP_001129121.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 103..122 4/18 (22%)
Forkhead 145..231 CDD:278670 46/87 (53%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 234..306 15/76 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 364..396 8/31 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG2294
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1270467at2759
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.820

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