Protein Alignment FoxK and FOXN2

DIOPT Version :10

• Sequence 1: NP_001261701.1
• Gene: FoxK / 39252
• FlyBaseID: FBgn0036134
• Length: 760
• Species: Drosophila melanogaster
• Sequence 2: NP_002149.2
• Gene: FOXN2 / 3344
• HGNCID: 5281
• Length: 431
• Species: Homo sapiens
• Alignment Length: 306
• Identity: 87/306 - (28%)
• Similarity: 140/306 - (45%)
• Gaps: 29/306 - (9%)

  Fly   440 FQTPSTASYNHNEKPPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKHYPYYRKETNKGWQNSIRH 504
            :|.|...|  ...|||||::.||..||..:|:|.|.:..|||:|:.|:||:..... ||:||:||
Human   101 YQNPEKKS--ATSKPPYSFSLLIYMAIEHSPNKCLPVKEIYSWILDHFPYFATAPT-GWKNSVRH 162

  Fly   505 NLSLNRYFIKVARSQDE-PGKGSFWRIDPDSGAKLIDHSYKKR--RQRSSQ-GFRPPYGMPRSAP 565
            |||||:.|.||.||..: .||||.|.:||:....|| .:.||:  ...||| |...|:.:  |:.
Human   163 NLSLNKCFQKVERSHGKVNGKGSLWCVDPEYKPNLI-QALKKQPFSSASSQNGSLSPHYL--SSV 224

  Fly   566 VSPSHMDNSRESSPLQDIVLQSAPGSPGMSLEQRAADPEIIYNSQNAHQQQQQQQQQQQQQT--- 627
            :..:.:.|.:||    ||...:|......|:||...:.|.....:.|.|:::.........:
Human   225 IKQNQVRNLKES----DIDAAAAMMLLNTSIEQGILECEKPLPLKTALQKKRSYGNAFHHPSAVR 285

  Fly   628 LSNNSNQYSSGSPYYVTNQSSGVATPQTHVEGSAASGGGGGGGVGALLALKRNHVMGGGASQHTL 692
            |..:.:..:|..|....|.|:.....|.....|:.|.......|...:. |.:||...|:
Human   286 LQESDSLATSIDPKEDHNYSASSMAAQRCASRSSVSSLSSVDEVYEFIP-KNSHVGSDGS----- 344

  Fly   693 HQQQAVAQQQHSEIIYEELPTDYSGHIEASEEECVTTATDATVAKR 738
               :....::.:::.||:.|...||:   :.:.|...:......|:
Human   345 ---EGFHSEEDTDVDYEDDPLGDSGY---ASQPCAKISEKGQSGKK 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA_FOXK	151..252	CDD:438740
		FH_FOXK	453..531	CDD:410800	40/78 (51%)
FOXN2	NP_002149.2	FH_FOXN2	111..192	CDD:410832	41/81 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	364..387		4/24 (17%)