DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxK and fd19B

DIOPT Version :9

Sequence 1:	NP_001261701.1	Gene:	FoxK / 39252	FlyBaseID:	FBgn0036134	Length:	760	Species:	Drosophila melanogaster
Sequence 2:	NP_608369.1	Gene:	fd19B / 33010	FlyBaseID:	FBgn0031086	Length:	260	Species:	Drosophila melanogaster

Alignment Length:	279	Identity:	86/279 - (30%)
Similarity:	127/279 - (45%)	Gaps:	64/279 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   388 ISIPKKEQKSPYLSPTGTISAANSCPASPRQGFIQNQPNNYNNYGNNNTQDLFQTPSTASYNHNE 452
            :|:.|||: || :|...:.|:.:||.:|                .:|::.|.....|      |.
  Fly    17 LSVDKKEE-SP-ISKHNSGSSFSSCSSS----------------SSNSSSDSMAAKS------NA 57

  Fly   453 KPPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKHYPYYRKETNKG-WQNSIRHNLSLNRYFIKVA 516
            ||.::|:.|||.||.::.:|:||||||..:|..::||||  |.|. ||||||||||||.:|::|.
  Fly    58 KPAFTYSALIVMAIWSSSEKRLTLSGICKWIADNFPYYR--TRKSVWQNSIRHNLSLNPFFVRVP 120

  Fly   517 RSQDEPGKGSFWRIDPDSGAKLIDHSYKKRRQRSSQ---GFRP-----PY-GMP------RSAPV 566
            |:.|:||:|.:|.:||.:....|..:..:.|:.:.|   |.||     || .||      .:.|.
  Fly   121 RALDDPGRGHYWALDPYAEDLSIGETTGRLRRSNWQQNTGARPKVTGHPYQRMPYYGHGHGNGPY 185

  Fly   567 SPSH------MDNSRESSPLQDIVLQSAPGSPGMSLEQRAADPEIIYNSQNAHQQQQQQQQQQQQ 625
            ..:|      ||:...::.:|.....       |...|....|         |..|.|.|.|...
  Fly   186 IKAHSAYFPIMDHQHHAAMVQHYQAM-------MHRYQMMPHP---------HHHQHQHQHQHPH 234

  Fly   626 QTLSNNSNQYSSGSPYYVT 644
            ......|.......||:.|
  Fly   235 SHFIQQSKPLHIQEPYHHT 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017
FoxK	NP_001261701.1	Forkhead	453..540	CDD:278670	44/87 (51%)
fd19B	NP_608369.1	FH	58..135	CDD:238016	42/78 (54%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445528
Domainoid	1	1.000	104	1.000	Domainoid score	I1720
eggNOG	1	0.900	-	-		E2759_KOG2294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	1	1.000	-	-		otm46522
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.750