Protein Alignment FoxK and foxk2a

DIOPT Version :9

• Sequence 1: NP_001261701.1
• Gene: FoxK / 39252
• FlyBaseID: FBgn0036134
• Length: 760
• Species: Drosophila melanogaster
• Sequence 2: NP_001184186.1
• Gene: foxk2a / 324141
• ZFINID: ZDB-GENE-030131-2861
• Length: 544
• Species: Danio rerio
• Alignment Length: 634
• Identity: 211/634 - (33%)
• Similarity: 269/634 - (42%)
• Gaps: 229/634 - (36%)

  Fly   169 AVTVIGRNSSTSLVHFNVAENNLVSRKHFQVLYDVELRA--FFVQCLSKNGIFVDDFLQRRNVDP 231
            :||| |||||...|..::..::.:||:|.::....|..|  |:::||.|||:|||...|||...|
Zfish    22 SVTV-GRNSSQGSVDVSMGHSSFISRRHLEIFSAGEDGAGEFYLRCLGKNGVFVDGAFQRRGAPP 85

  Fly   232 LRLPQRCYFRFPSTEIRIEFESYVPATSSDAIDGHSPSLVVGGGGGVAGGGAHVIITPLPRDELH 296
            |:||:.|..|||||.|:|.|
Zfish    86 LQLPRACTLRFPSTNIKISF--------------------------------------------- 105

  Fly   297 QQQLHHHQQQPHLQQQQHPHHPPAHHLPLQQQQQQQQPAHHPLPHTPHHPLHHTAL-HQQQQRSG 360
                                                                 ||| ..|::..|
Zfish   106 -----------------------------------------------------TALCSDQRECRG 117

  Fly   361 SIVVAPPAGAAAHLIAGDGPGIYSPLKISIPKK--EQKSPYLSPTGTISAANSCPASPRQGFIQN 423
            ::.|  |..|.           .|||.||||:.  ..:||..|||||||||||||:|||...:.:
Zfish   118 ALEV--PVKAQ-----------ISPLTISIPENITHLRSPLPSPTGTISAANSCPSSPRGAGLSS 169

  Fly   424 QPNNYNNYGNNNTQDLFQTPSTA----------SYNHNEKPPYSYAQLIVQAISAAPDKQLTLSG 478
            .     ..|...|.:|....|.:          |...:.||||||||||||||:.||||||||:|
Zfish   170 Y-----RMGRGLTAELINENSQSEIDKEASGGDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNG 229

  Fly   479 IYSFIVKHYPYYRKETNKGWQNSIRHNLSLNRYFIKVARSQDEPGKGSFWRIDPDSGAKLIDHSY 543
            ||:.|.|:||||| ..:||||||||||||||||||||||||:||||||||||||.|..||:|.::
Zfish   230 IYTHITKNYPYYR-TADKGWQNSIRHNLSLNRYFIKVARSQEEPGKGSFWRIDPSSEGKLMDQAF 293

  Fly   544 KKRRQRSSQGFRPPYG--MPRSAPVSPSHM-------------DNSRESSPLQDIVLQSAPGSPG 593
            :|||.|....||.|.|  ..||||.||:|.             |:|||.|||.   |:..|.:
Zfish   294 RKRRPRGVPCFRTPLGPLSSRSAPASPTHTGVLSAHSSGVQTPDSSREGSPLP---LEPEPSA-- 353

  Fly   594 MSLEQRAADPEIIYNSQNAHQQQQQQQQQQQQQTLSNNSNQYSSGSPYYVTNQ----------SS 648
                  ||.|             |.:....|:...:.|    :.|||..:..|          |.
Zfish   354 ------AAAP-------------QPKLAVIQESCFTQN----TPGSPVLIAVQQPLQQSLKPVSF 395

  Fly   649 GVATPQTHVEGSAASGGGGGGGVGALLALKRNHVMGGGASQHTLHQQQAV----AQQQHSEIIYE 709
            .||||.:    |||.                ..||   .:.|.|||..|.    |:||:.:
Zfish   396 SVATPAS----SAAP----------------QPVM---QTLHLLHQIPAACVFRAEQQNGD---- 433

  Fly   710 ELPTDYSGHIEASEEECVTTATDATVAKRPKYVSEVLXCVRIQKHRQNK 758
                        ::|..||......||..|...|.|| .:.:....|::
Zfish   434 ------------AQEVKVTVEPVPAVAAAPGASSRVLQPLAVAPRGQHQ 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017	39/84 (46%)
		Forkhead	453..540	CDD:278670	71/86 (83%)
foxk2a	NP_001184186.1	FHA	16..105	CDD:238017	38/83 (46%)
		Forkhead	204..290	CDD:278670	71/86 (83%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	147	1.000	Domainoid score	I4448
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	309	1.000	Inparanoid score	I2594
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	1	1.000	-	-		otm26388
orthoMCL	1	0.900	-	-		OOG6_104629
Panther	1	1.100	-	-	O	PTHR45881
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2114
SonicParanoid	1	1.000	-	-		X1668
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.860