DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxK and Foxs1

DIOPT Version :9

Sequence 1:	NP_001261701.1	Gene:	FoxK / 39252	FlyBaseID:	FBgn0036134	Length:	760	Species:	Drosophila melanogaster
Sequence 2:	NP_001012091.1	Gene:	Foxs1 / 311547	RGDID:	1310679	Length:	327	Species:	Rattus norvegicus

Alignment Length:	231	Identity:	76/231 - (32%)
Similarity:	104/231 - (45%)	Gaps:	36/231 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   441 QTPSTAS----YNHNEKPPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKHYPYYRKETNKGWQNS 501
            |.|.||.    .....||||||..||..||.::|.::.||||||.:|:..:.:|| ....|||||
  Rat     2 QQPPTAESLAPSTEPSKPPYSYIALIAMAIQSSPGQRATLSGIYRYIMGRFAFYR-HNRPGWQNS 65

  Fly   502 IRHNLSLNRYFIKVARSQDEPGKGSFWRIDPDSGAKLIDHSYKKRRQR-----SSQGFRPPYGMP 561
            ||||||||..|:||.|...:|||||:|.:|||........|:.:||:|     .:||.:
  Rat    66 IRHNLSLNECFVKVPRDDRKPGKGSYWTLDPDCHDMFQHGSFLRRRRRFTKRTGAQGTK------ 124

  Fly   562 RSAPVSPSHMDNSRESSPLQDIVLQSAPGSPGMSLEQRAADPEIIYN---------SQNAHQQQQ 617
              .||...|.. .|.:||.|        |:|..:..:....|..:.|         |..|:....
  Rat   125 --GPVKADHRP-LRATSPDQ--------GAPNTTTGRLCPFPPEVPNPKGFGGLMGSLPANMCPT 178

  Fly   618 QQQQQQQQQTLSNNSNQYSSGSPYYVTNQSSGVATP 653
            ....:.|..|...:.....||.|..::..:|....|
  Rat   179 TSDTRPQLPTGPKDMCSAKSGGPRELSEATSPSPCP 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017
FoxK	NP_001261701.1	Forkhead	453..540	CDD:278670	46/86 (53%)
Foxs1	NP_001012091.1	Forkhead	18..103	CDD:278670	46/85 (54%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820