DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxK and Foxi1

DIOPT Version :9

Sequence 1:	NP_001261701.1	Gene:	FoxK / 39252	FlyBaseID:	FBgn0036134	Length:	760	Species:	Drosophila melanogaster
Sequence 2:	NP_001099246.1	Gene:	Foxi1 / 287185	RGDID:	1307421	Length:	372	Species:	Rattus norvegicus

Alignment Length:	285	Identity:	83/285 - (29%)
Similarity:	134/285 - (47%)	Gaps:	64/285 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   397 SPYLSPTGT-------ISAANSCPASPRQGFIQNQ--PNNYNNYGNNNTQDLFQTPSTASYNHNE 452
            :|||...||       :...|:.|..|:...:|.|  |:...         ....||........
  Rat    61 NPYLWLNGTAMTPPPYLPGTNASPFLPQAYGMQRQLLPSELG---------WLPIPSQEELMKLV 116

  Fly   453 KPPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKHYPYYRKETNKGWQNSIRHNLSLNRYFIKVAR 517
            :|||||:.||..||..|||::||||.||.::..::|:|.| :..|||||||||||||..|.||.|
  Rat   117 RPPYSYSALIAMAIHGAPDQRLTLSQIYQYVADNFPFYNK-SKAGWQNSIRHNLSLNDCFKKVPR 180

  Fly   518 SQDEPGKGSFWRIDPDSGAKLIDH-SYKKRRQRSSQGFRPPYGMPRSAPVSPSHMDNSRESSPLQ 581
            .:|:||||::|.:||:. .|:.|: :::::|:|.|..               |....|..|...:
  Rat   181 DEDDPGKGNYWTLDPNC-EKMFDNGNFRRKRKRKSDA---------------SSSTGSLASEKTE 229

  Fly   582 DIVLQSAPGSPGMSLEQRAADPEIIYNSQNAHQQQQQQQQQQQQQTLSNNSNQYSSGSPYYVTNQ 646
            :.:|.|:|         :..:|:.:.::.:             ..|.|::..:.||.:|......
  Rat   230 NRLLSSSP---------KPTEPQEVLDTAS-------------PDTTSSSPEKRSSPAPSGTPCL 272

  Fly   647 SSGVATPQTHVEG------SAASGG 665
            ::.::|...:|.|      |||:.|
  Rat   273 NNFLSTMTAYVNGTNPISRSAATPG 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017
FoxK	NP_001261701.1	Forkhead	453..540	CDD:278670	47/86 (55%)
Foxi1	NP_001099246.1	FH	117..205	CDD:214627	48/89 (54%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820