DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment FoxK and FOXR1

DIOPT Version :10

Sequence 1:NP_001261701.1 Gene:FoxK / 39252 FlyBaseID:FBgn0036134 Length:760 Species:Drosophila melanogaster
Sequence 2:XP_016873064.1 Gene:FOXR1 / 283150 HGNCID:29980 Length:297 Species:Homo sapiens


Alignment Length:286 Identity:57/286 - (19%)
Similarity:101/286 - (35%) Gaps:98/286 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   322 HLPLQQQQQQQ------QPAHHPLPHTPHHPLHHTALHQQQQRSGSIVVAPPAGAAAHLIAGDGP 380
            ||||.:|:..:      :|...||...|:                     |..         |||
Human    13 HLPLAEQKLARYKLRIVKPPKLPLEKKPN---------------------PDK---------DGP 47

  Fly   381 G-------------IYSPLKISI------------------PKKEQKSPYLSPTG--TISAANSC 412
            .             :|.|.|:.:                  |:||:.:......|  ::|.::|.
Human    48 DYEPNLWMWVNPNIVYPPGKLEVSGRRKREDLTSTLPSSQPPQKEEDASCSEAAGVESLSQSSSK 112

  Fly   413 PASPRQGFIQNQPNNYNNYGNNNTQDLFQTPSTASYNHNE---------------------KPPY 456
            .:.||:.|..: |:.:........:|...:.|.|..:.::                     :||.
Human   113 RSPPRKRFAFS-PSTWELTEEEEAEDQEDSSSMALPSPHKRAPLQSRRLRQASSQAGRLWSRPPL 176

  Fly   457 SYAQLIVQAISAAPDKQLTLSGIYSFIVKHYPYYRKETNKGWQNSIRHNLSLNRYFIKVARSQD- 520
            :|..||..|:..:....|.:..||||..||:|::| ...:||:|::||||.....|.||..|.. 
Human   177 NYFHLIALALRNSSPCGLNVQQIYSFTRKHFPFFR-TAPEGWKNTVRHNLCFRDSFEKVPVSMQG 240

  Fly   521 ----EPGKGSFWRIDPDSGAKLIDHS 542
                .| :...|::..:...:..:.:
Human   241 GASTRP-RSCLWKLTEEGHRRFAEEA 265

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FoxKNP_001261701.1 FHA_FOXK 151..252 CDD:438740
FH_FOXK 453..531 CDD:410800 28/82 (34%)
FOXR1XP_016873064.1 FH_FOXR 171..259 CDD:410810 28/89 (31%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.