DRSC/TRiP Functional Genomics Resources

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Protein Alignment FoxK and Foxi2

DIOPT Version :9

Sequence 1:NP_001261701.1 Gene:FoxK / 39252 FlyBaseID:FBgn0036134 Length:760 Species:Drosophila melanogaster
Sequence 2:NP_899016.2 Gene:Foxi2 / 270004 MGIID:3028075 Length:311 Species:Mus musculus


Alignment Length:389 Identity:101/389 - (25%)
Similarity:153/389 - (39%) Gaps:120/389 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   337 HPLPHTPHHPLHH--TALHQQQQ---RSGSIVVAPPAGAAAHLIAGDGPG-IYSPLKISIPKKEQ 395
            |.|.....||..:  |.|...::   .|.::..||.|       .|.||. .|:...:::|    
Mouse    15 HGLTRAIAHPPSYGRTDLSSGRRLWVNSAALSPAPYA-------TGPGPAPSYAAATLAVP---- 68

  Fly   396 KSPYLSPTGTISAANSCPASPRQGFIQNQPNNYNNYGNNNTQDLFQTPSTASYNHNEKPPYSYAQ 460
             ...|..:|.::.|:....|     :..|            |:|.:.         .:|||||:.
Mouse    69 -GSLLGASGGLAGADLAWLS-----LSGQ------------QELLRL---------VRPPYSYSA 106

  Fly   461 LIVQAISAAPDKQLTLSGIYSFIVKHYPYYRKETNKGWQNSIRHNLSLNRYFIKVARSQDEPGKG 525
            ||..||.:||.::||||.||.::..::|:| |.:..|||||||||||||..|.||.|.:::||||
Mouse   107 LIAMAIQSAPLRRLTLSQIYQYVAGNFPFY-KRSKAGWQNSIRHNLSLNDCFKKVPRDENDPGKG 170

  Fly   526 SFWRIDPDSGAKLIDH-SYKKRRQRSSQGFRPPYGMPRSAPVSPSHMDNSRESSPLQDIVLQSAP 589
            ::|.:||:. .|:.|: :::::|:|..:                           ..:..:..|.
Mouse   171 NYWTLDPNC-EKMFDNGNFRRKRRRRGE---------------------------TSEAAVPGAS 207

  Fly   590 GSPGMSLEQRAADPEIIYNSQNAHQQQQQQQQQQQQQTLSNNSNQYSSGSPYYVTNQSSGVATPQ 654
            ...|.:||.|.:.|                   |..||         |.||...|.         
Mouse   208 SPEGTALEPRGSTP-------------------QDPQT---------SPSPSEATT--------- 235

  Fly   655 THVEGSAASGGGGGGGVGALLALKRNHVMGGGASQHTLHQQQAVAQQQHSEIIYEELPTDYSGH 718
            |.:.|.:.:.|...||.|||        ..|.|...:|.:....| ..||..|....|....||
Mouse   236 TCLSGFSTAMGALAGGFGAL--------PDGLAHDFSLRRPPPTA-AAHSPQIPNTAPGFAPGH 290

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FoxKNP_001261701.1 FHA <170..253 CDD:238017
Forkhead 453..540 CDD:278670 45/86 (52%)
Foxi2NP_899016.2 Forkhead 99..184 CDD:333958 45/86 (52%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 188..237 15/112 (13%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 263..294 8/29 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG2294
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1270467at2759
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
54.820

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