DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxK and sep1

DIOPT Version :9

Sequence 1:	NP_001261701.1	Gene:	FoxK / 39252	FlyBaseID:	FBgn0036134	Length:	760	Species:	Drosophila melanogaster
Sequence 2:	NP_596301.1	Gene:	sep1 / 2540866	PomBaseID:	SPBC4C3.12	Length:	663	Species:	Schizosaccharomyces pombe

Alignment Length:	235	Identity:	77/235 - (32%)
Similarity:	112/235 - (47%)	Gaps:	51/235 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   439 LFQTPSTASYNHNE------------KPPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKHYPYYR 491
            :::.||.:|....|            |||||||.||..:|..:||::||||.||.:|...:.:|.
pombe   102 IYRNPSVSSSQSQEPEEFFLPLDDGKKPPYSYAMLIGMSIIRSPDRRLTLSAIYDWISNTFSFYN 166

  Fly   492 KETNKGWQNSIRHNLSLNRYFIKVARSQDEPGKGSFWRIDPDSGAKLIDHSYKKRRQRSSQGFRP 556
            | :|.|||||||||||||:.|:|:.|.::.||||.||.|.|..     :..:.|.:.|     :|
pombe   167 K-SNNGWQNSIRHNLSLNKAFMKIERPRNLPGKGHFWSIRPGH-----EEQFLKLKLR-----KP 220

  Fly   557 PYGMPRSAPVSPSHMDNSRESSPLQDIVLQ----SAPGSPGMSLEQRAADPEIIYNSQNAHQQQQ 617
              |:            |||.:.|:||:...    |:.||.|.:....:..   |:|.::.:.|..
pombe   221 --GV------------NSRPAPPVQDVTSSTKYGSSTGSSGFNTFNTSPH---IFNQRHQYLQNY 268

  Fly   618 QQQQQQQQQTLSN----NSNQYSSGSPYYVTNQSSGVATP 653
            .........|:||    |.:...|..||..|   .|:..|
pombe   269 YTASLTNIPTISNVNATNFHPLHSQQPYVDT---PGIDAP 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017
FoxK	NP_001261701.1	Forkhead	453..540	CDD:278670	46/86 (53%)
sep1	NP_596301.1	COG5025	20..663	CDD:227358	77/235 (33%)
sep1	NP_596301.1	Forkhead	128..214	CDD:278670	46/91 (51%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	104	1.000	Domainoid score	I1720
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2114
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.930