DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxK and Foxi3

DIOPT Version :9

Sequence 1:	NP_001261701.1	Gene:	FoxK / 39252	FlyBaseID:	FBgn0036134	Length:	760	Species:	Drosophila melanogaster
Sequence 2:	NP_001094934.1	Gene:	Foxi3 / 232077	MGIID:	3511278	Length:	399	Species:	Mus musculus

Alignment Length:	401	Identity:	116/401 - (28%)
Similarity:	160/401 - (39%)	Gaps:	107/401 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   333 QPAHHP-LPHTPHHPLHHTALHQQQQRSGSIVVAPPAGAAAHLIAGDGPGIYSPLKISI------ 390
            |||..| .|.|...|.           ..|...||||.||...:..:|||:..|...:.
Mouse    13 QPAAAPGAPPTSRAPY-----------GLSDYAAPPAAAANPYLWLNGPGVGGPASAASYLGAPP 66

  Fly   391 -PKKEQKSPYLSP---TGTISAAN--------SCPASPRQGFIQNQPNNYNNYGNNNTQDLFQTP 443
             |......|:|.|   .||.:.|.        |.||||..   ...|.........:.:||.:.
Mouse    67 PPPGAAPGPFLQPPAAPGTFAGAQRGFAQPSASAPASPAG---SAAPGELGWLSMASREDLMKM- 127

  Fly   444 STASYNHNEKPPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKHYPYYRKETNKGWQNSIRHNLSL 508
                    .:|||||:.||..||.:||:::||||.||.|:..::|:|:: :..||||||||||||
Mouse   128 --------VRPPYSYSALIAMAIQSAPERKLTLSHIYQFVADNFPFYQR-SKAGWQNSIRHNLSL 183

  Fly   509 NRYFIKVARSQDEPGKGSFWRIDPDSGAKLIDHS--YKKRRQR--SSQGFRPPYGMPRS------ 563
            |..|.||.|.:|:||||::|.:||:. .|:.|:.  .:|||:|  :|.....|.|..:|
Mouse   184 NDCFKKVPRDEDDPGKGNYWTLDPNC-EKMFDNGNFRRKRRRRAEASSNLTVPSGTSKSEGQSSR 247

  Fly   564 ----------APVS---PSHMDNSRESSPLQDIVLQSAPGSPGMSLEQRAADPEI-----IYNSQ 610
                      :|.|   ||......|.:       :|...|||.|  ...:.|.:     .:|:.
Mouse   248 LRVSGKLEGDSPSSILRPSQSPEPPEGT-------KSTASSPGAS--TLTSTPCLNTFLSTFNTL 303

  Fly   611 NAHQQQQQQQQ-------------QQQQQTLSNNSNQYSSGSPYYV-----TNQSSGVATPQTHV 657
            |.:.......|             |....|..|.|...||.....:     :||.|....|
Mouse   304 NVNSSSSMGNQRTLPGSRRHLGGTQLPSSTFPNTSVPDSSPDSMQLSTVGGSNQLSSYYNP---- 364

  Fly   658 EGSAASGGGGG 668
                .|||..|
Mouse   365 ----FSGGSSG 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017
FoxK	NP_001261701.1	Forkhead	453..540	CDD:278670	46/86 (53%)
Foxi3	NP_001094934.1	Forkhead	129..215	CDD:278670	46/87 (53%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920