Protein Alignment FoxK and FOXL1

DIOPT Version :10

• Sequence 1: NP_001261701.1
• Gene: FoxK / 39252
• FlyBaseID: FBgn0036134
• Length: 760
• Species: Drosophila melanogaster
• Sequence 2: NP_005241.1
• Gene: FOXL1 / 2300
• HGNCID: 3817
• Length: 345
• Species: Homo sapiens
• Alignment Length: 366
• Identity: 98/366 - (26%)
• Similarity: 148/366 - (40%)
• Gaps: 101/366 - (27%)

  Fly   367 PAGAAAHLIAGDGPGIYSPLKISIPKKEQKSPYLSPTGTISAANSCPASPRQGFIQNQPNNYNNY 431
            ||.||:.::.     :|.|.:..:|..      .:|...::|:...
Human    10 PALAASPMLY-----LYGPERPGLPLA------FAPAAALAASGRA------------------- 44

  Fly   432 GNNNTQDLFQTPSTASYNHNEKPPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKHYPYYRKETNK 496
                     :||        :||||||..||..||..||::::||:|||.||:..:|:|. :..:
Human    45 ---------ETP--------QKPPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYH-DNRQ 91

  Fly   497 GWQNSIRHNLSLNRYFIKVARSQDEPGKGSFWRIDPDSGAKLIDHSYKKRRQRSSQGFRPPYGMP 561
            |||||||||||||..|:||.|.:..|||||:|.:||.......:.:|::|:::.    :|..|.|
Human    92 GWQNSIRHNLSLNDCFVKVPREKGRPGKGSYWTLDPRCLDMFENGNYRRRKRKP----KPGPGAP 152

  Fly   562 -----------RSAPVSPSHMDNSRESSPLQDIVLQSAPGSPGMSLEQRAADPEIIYNSQNAHQQ 615
                       |||...|.....:..|.|... .||:||..|...|: ..:.|..::....|...
Human   153 EAKRPRAETHQRSAEAQPEAGSGAGGSGPAIS-RLQAAPAGPSPLLD-GPSPPAPLHWPGTASPN 215

  Fly   616 QQQQQQQQQQQTLSNNSNQYSS---GSPYYVTNQSSGVATP----------------QTHVEGSA 661
            :......|....::......:.   |||....::||..::.                |....|..
Human   216 EDAGDAAQGAAAVAVGQAARTGDGPGSPLRPASRSSPKSSDKSKSFSIDSILAGKQGQKPPSGDE 280

  Fly   662 ASGG---GGGGGVGA-LLALKRN-------------HVMGG 685
            ..||   |.||.:|| |||...:             ||.||
Human   281 LLGGAKPGPGGRLGASLLAASSSLRPPFNASLMLDPHVQGG 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA_FOXK	151..252	CDD:438740
		FH_FOXK	453..531	CDD:410800	44/77 (57%)
FOXL1	NP_005241.1	FH_FOXL1	47..144	CDD:410801	49/105 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	136..289		29/158 (18%)