Protein Alignment FoxK and FOXF1

DIOPT Version :10

• Sequence 1: NP_001261701.1
• Gene: FoxK / 39252
• FlyBaseID: FBgn0036134
• Length: 760
• Species: Drosophila melanogaster
• Sequence 2: NP_001442.2
• Gene: FOXF1 / 2294
• HGNCID: 3809
• Length: 379
• Species: Homo sapiens
• Alignment Length: 324
• Identity: 90/324 - (27%)
• Similarity: 134/324 - (41%)
• Gaps: 85/324 - (26%)

  Fly   444 STASYNHNEKPPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKHYPYYRKETNKGWQNSIRHNLSL 508
            :.|.....|||||||..|||.||.::|.|:||||.||.|:...:|::| .:.:||:||:||||||
Human    39 TNAGIRRPEKPPYSYIALIVMAIQSSPTKRLTLSEIYQFLQSRFPFFR-GSYQGWKNSVRHNLSL 102

  Fly   509 NRYFIKVARSQDEPGKGSFWRIDPDSGAKLIDHSYKKRR---QRSSQGFRPPYGMPRSAPVSPSH 570
            |..|||:.:....||||.:|.|||.|.....:.|:::|.   :|..|..:|.|.|...  :..:|
Human   103 NECFIKLPKGLGRPGKGHYWTIDPASEFMFEEGSFRRRPRGFRRKCQALKPMYSMMNG--LGFNH 165

  Fly   571 MDNSRE--------SSPLQDIVLQSA--------PGS-PGMSLEQRAADPEIIYNSQNAHQQQQQ 618
            :.::..        |.|...:.|:..        ||: .||:|...:. |.:
Human   166 LPDTYGFQGSAGGLSCPPNSLALEGGLGMMNGHLPGNVDGMALPSHSV-PHL------------- 216

  Fly   619 QQQQQQQQTLSNNSNQYSSG------------------SPYYVTNQSSGVATPQTHVEGSAAS-- 663
                     .||..:.|..|                  ||...|. :.||..|.....||||:
Human   217 ---------PSNGGHSYMGGCGGAAAGEYPHHDSSVPASPLLPTG-AGGVMEPHAVYSGSAAAWP 271

  Fly   664 -GGGGGGGVGALLALKRN---------HVMGGGASQHTLHQQQAVAQQQHSEIIYEELPTDYSG 717
             ........||.. :|:.         :.:.|..|.|:| :|..:.|..|:      .|.:..|
Human   272 PSASAALNSGASY-IKQQPLSPCNPAANPLSGSLSTHSL-EQPYLHQNSHN------APAELQG 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA_FOXK	151..252	CDD:438740
		FH_FOXK	453..531	CDD:410800	41/77 (53%)
FOXF1	NP_001442.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..45		1/5 (20%)
		FH_FOXF1	49..147	CDD:410823	46/98 (47%)