| Sequence 1: | NP_001261701.1 | Gene: | FoxK / 39252 | FlyBaseID: | FBgn0036134 | Length: | 760 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001032242.1 | Gene: | FOXK1 / 221937 | HGNCID: | 23480 | Length: | 733 | Species: | Homo sapiens |
| Alignment Length: | 668 | Identity: | 216/668 - (32%) |
|---|---|---|---|
| Similarity: | 281/668 - (42%) | Gaps: | 236/668 - (35%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 117 PPATSSTTNSSSSSTTSANTNNPS-----------ANAASTLTSSSPPYGELRFNQ-EVLPITDA 169
Fly 170 VTVIGRNSSTSLVHFNVAENNLVSRKHFQVLYDVELRAFFVQCLSKNGIFVDDFLQRRNVDPLRL 234
Fly 235 PQRCYFRFPSTEIRIEFESYVPATSSDAIDGHSPSLVVGGGGGVAGGGAHVIITPLPRDELHQQQ 299
Fly 300 LHHHQQQPHLQQQQHPHHPPAHHLPLQQQQQQQQPAHHPLPHTPHHPLHHTALHQQQQRSGSIVV 364
Fly 365 APPAGAAAHLIAGDGPGIYSPLKISIPKKEQK---SPYLSPTGTISAANSCPASPRQG------F 420
Fly 421 IQNQPNNYNNYGNNNTQDL---------------FQTPSTASYNHNEKPPYSYAQLIVQAISAAP 470
Fly 471 DKQLTLSGIYSFIVKHYPYYRKETNKGWQNSIRHNLSLNRYFIKVARSQDEPGKGSFWRIDPDSG 535
Fly 536 AKLIDHSYKKRRQRSSQGFRPPYG--MPRSAPVSPSHMD--------------NSRESSPL---- 580
Fly 581 ----------QDIVLQSAPGSPG------MSLEQRAAD---------PEIIYNSQ----NAHQQQ 616
Fly 617 QQQQQQQQQQTLSNNSNQYSSGSPYYVTNQSSGVATPQTHVEGSAASGGGGGGGVGALLALKRNH 681
Fly 682 VMGGGASQHTLHQQQAVA 699 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| FoxK | NP_001261701.1 | FHA | <170..253 | CDD:238017 | 38/82 (46%) |
| Forkhead | 453..540 | CDD:278670 | 71/86 (83%) | ||
| FOXK1 | NP_001032242.1 | Interaction with SIN3A and SIN3B. /evidence=ECO:0000250|UniProtKB:P42128 | 2..40 | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 36..79 | 5/20 (25%) | |||
| Required for interaction with FOXO4 and MEF2C. /evidence=ECO:0000250|UniProtKB:P42128 | 95..420 | 171/450 (38%) | |||
| FHA | <102..204 | CDD:224630 | 43/150 (29%) | ||
| FHA | 110..203 | CDD:238017 | 40/95 (42%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 287..306 | 2/18 (11%) | |||
| Forkhead | 305..391 | CDD:278670 | 71/86 (83%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 413..436 | 7/22 (32%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 676..733 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 145 | 1.000 | Domainoid score | I4581 |
| eggNOG | 1 | 0.900 | - | - | E2759_KOG2294 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 296 | 1.000 | Inparanoid score | I2745 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D1270467at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000010 | |
| OrthoInspector | 1 | 1.000 | - | - | otm40458 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_104629 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR45881 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R2114 |
| SonicParanoid | 1 | 1.000 | - | - | X1668 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 13 | 12.860 | |||||