DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxK and fkh-2

DIOPT Version :9

Sequence 1:	NP_001261701.1	Gene:	FoxK / 39252	FlyBaseID:	FBgn0036134	Length:	760	Species:	Drosophila melanogaster
Sequence 2:	NP_508644.1	Gene:	fkh-2 / 180663	WormBaseID:	WBGene00001434	Length:	270	Species:	Caenorhabditis elegans

Alignment Length:	250	Identity:	81/250 - (32%)
Similarity:	120/250 - (48%)	Gaps:	79/250 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   405 TISAANSCPASPRQGFIQNQPNNYNNYGNNNTQDLFQTPSTASYNHNEKPPYSYAQLIVQAISAA 469
            |:|..:..|:|                  :|:::  :|||:.    |:|||:||..||:.||..:
Worm    69 TLSKDSKSPSS------------------SNSEE--KTPSSP----NDKPPFSYNALIMMAIKDS 109

  Fly   470 PDKQLTLSGIYSFIVKHYPYYRKETNKGWQNSIRHNLSLNRYFIKVARSQDEPGKGSFWRID--- 531
            |:|:|||:|||.:||.:||:|| :..:|||||||||||||:.|:||.|:.|:||||::|.:|
Worm   110 PEKRLTLAGIYEYIVTNYPFYR-DNKQGWQNSIRHNLSLNKCFVKVPRNFDDPGKGNYWMLDATA 173

  Fly   532 ----------------PDSGAKLIDHSYKKRRQRSSQGFRPPYGMPRSAPVSPSH----MDNS-- 574
                            |.|.::....:||:....::..|  ||..| ..|..|.|    ..|.
Worm   174 EDEVFIGGATGKLRRRPSSLSRARMDAYKQYGAAAANLF--PYFSP-GMPALPRHPYLTAPNGFL 235

  Fly   575 -RESSPLQDIVLQSAPGSPGMSLEQRAADPEIIYNSQNAHQQQQQQQQQQQQQTL 628
             |:..|:        |..|     |..|.||::            |....|||:|
Worm   236 PRQMMPI--------PAMP-----QVFAQPELL------------QLYINQQQSL 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017
FoxK	NP_001261701.1	Forkhead	453..540	CDD:278670	49/105 (47%)
fkh-2	NP_508644.1	FH	93..170	CDD:238016	46/77 (60%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920